{"id":"W2120386009","doi":"10.1007/s10549-015-3342-2","title":"Overall survival (OS) endpoint: an incomplete evaluation of metastatic breast cancer (MBC) treatment outcome","year":2015,"lang":"en","type":"review","venue":"Breast Cancer Research and Treatment","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Internal medicine; Metastatic breast cancer; Clinical trial; Oncology; Progression-free survival; Breast cancer; Chemotherapy; Clinical endpoint; Cancer; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001554903,0.001052954,0.003764723,0.0007639128,0.0002229833,0.00007204782,0.000227162,0.000254107,0.003173001],"category_scores_gemma":[0.00001334695,0.0006780957,0.0006042205,0.0006001817,0.000403652,0.0001900833,0.0001274811,0.0003904557,0.00004883487],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.01114716,"about_ca_system_score_gemma":0.006886896,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03184845,"about_ca_topic_score_gemma":0.006666518,"domain_scores_codex":[0.9930201,0.00154231,0.0010959,0.00125382,0.002014834,0.001073092],"domain_scores_gemma":[0.9959071,0.0002937703,0.0004712824,0.0008681644,0.0013786,0.001081123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002003925,0.004242673,0.002493601,0.003021352,0.005751782,0.0001560549,0.0002809367,0.000007393397,0.000006541751,0.00007639031,0.0003302348,0.9816291],"study_design_scores_gemma":[0.03782685,0.01145868,0.01574861,0.005862734,0.03865169,0.001676706,0.000206246,0.0002050102,0.00002778067,0.0003216574,0.8867623,0.001251731],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007655107,0.9712751,7.693217e-7,0.0007821253,0.0004194342,0.006072688,0.01303682,0.00005316833,0.0007047987],"genre_scores_gemma":[0.008573545,0.9796813,0.00005151175,0.00002313439,0.0008580909,0.007126024,0.001699174,0.0001426742,0.001844614],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9803774,"threshold_uncertainty_score":0.999567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5563596854227307,"score_gpt":0.5889062232591702,"score_spread":0.03254653783643946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}