{"id":"W2120403234","doi":"10.1534/genetics.109.107631","title":"Telomerase Is Essential to Alleviate Pif1-Induced Replication Stress at Telomeres","year":2009,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Oncosuisse; European Commission; Canadian Institutes of Health Research; Genome Canada; Seventh Framework Programme; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Telomere; Telomerase; DNA replication; DNA damage; Replication protein A; Molecular biology; Genetics; Control of chromosome duplication; DNA; Cell biology; Gene; DNA-binding protein; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001051552,0.0003818832,0.0002673485,0.0002243008,0.0001522604,0.0003956131,0.0002155682,0.0002629529,0.0007916137],"category_scores_gemma":[0.000234462,0.0001563937,0.0001913078,0.0001654323,0.0001747443,0.0002155472,0.0002866657,0.0004219114,0.0003718749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003593303,"about_ca_system_score_gemma":0.0002277502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005213284,"about_ca_topic_score_gemma":0.0006299654,"domain_scores_codex":[0.9999125,0.000009452864,0.000008362595,0.00001859326,0.00003011509,0.00002100116],"domain_scores_gemma":[0.9998634,0.00002004848,0.00004215746,0.00001812331,0.00001708616,0.00003915453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003372865,0.000006247074,0.0002066479,0.00001942217,0.000002107496,0.00003312284,0.000005027464,0.000046931,0.9986554,0.00004591863,0.0000185716,0.0009268097],"study_design_scores_gemma":[0.00000915024,0.00006695809,0.005171492,0.000008857061,0.00001163305,0.0003880024,0.00001660235,0.0008458777,0.9907155,0.0001112136,0.002650087,0.000004743629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940082,0.002309935,0.002314997,0.0001091544,0.0000188752,0.000009120986,0.0003331414,0.0001202062,0.0007763788],"genre_scores_gemma":[0.9949952,0.0008348771,0.001898335,0.00002490728,0.000006382751,0.000009471324,0.0006861693,0.00003341377,0.001511276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007916137,"threshold_uncertainty_score":0.002648175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01205218621519062,"score_gpt":0.2763981506213734,"score_spread":0.2643459644061828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}