{"id":"W2120443279","doi":"10.1261/rna.554607","title":"The impact of alternative splicing in vivo: Mouse models show the way","year":2007,"lang":"en","type":"review","venue":"RNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Biology; Alternative splicing; RNA splicing; Proteome; Computational biology; Gene isoform; Function (biology); Gene; Phenotype; In vivo; Minigene; Cell biology; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008002509,0.0002369633,0.0004677569,0.00006962475,0.00008875156,0.00003463512,0.0006544198,0.0001821979,0.000006703737],"category_scores_gemma":[0.00009748169,0.0001091069,0.0004631646,0.0001595148,0.0001047436,0.000003128014,0.0001960809,0.0003416743,0.000003303779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007465938,"about_ca_system_score_gemma":0.0001983959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000866142,"about_ca_topic_score_gemma":0.0001904372,"domain_scores_codex":[0.9985996,0.0001660619,0.0003637364,0.0002581192,0.0002066233,0.0004058763],"domain_scores_gemma":[0.9989654,0.000131583,0.0001973194,0.0005732903,0.00006458819,0.00006774854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005840906,0.00004129056,0.00000952689,0.0006878446,0.0004396797,0.00001260426,0.00005957895,0.0008732945,0.01596969,0.0002164963,0.001298445,0.9803331],"study_design_scores_gemma":[0.0009088244,0.001015911,0.00002120572,0.006116486,0.0002117476,0.00009171168,0.0001852297,0.006434658,0.04305967,0.0004821991,0.9402341,0.001238248],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0154351,0.9815295,0.0002863937,0.00001122939,0.00003653854,0.0004999762,0.0000464056,0.000002899956,0.00215194],"genre_scores_gemma":[0.007153228,0.9897813,0.00001770124,0.00001036367,0.0001789836,0.0000292079,0.00001725252,0.00003447512,0.002777467],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9790949,"threshold_uncertainty_score":0.4449251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06092173989011637,"score_gpt":0.3899559802467745,"score_spread":0.3290342403566581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}