{"id":"W2120470565","doi":"10.1128/aac.49.10.4375-4378.2005","title":"Interaction of the MexA and MexB Components of the MexAB-OprM Multidrug Efflux System of <i>Pseudomonas aeruginosa</i> : Identification of MexA Extragenic Suppressors of a T578I Mutation in MexB","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Efflux; Pseudomonas aeruginosa; Mutation; Biology; Genetics; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002882,0.0002819182,0.000192933,0.0002079362,0.000149515,0.0002754965,0.0002317112,0.0002062521,0.001069027],"category_scores_gemma":[0.0001973351,0.0001363849,0.0001889658,0.0001109894,0.0002552365,0.0001084335,0.0002737071,0.0004474679,0.0004258915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176744,"about_ca_system_score_gemma":0.0002466622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001260984,"about_ca_topic_score_gemma":0.001039943,"domain_scores_codex":[0.9998522,0.00002432859,0.00001389123,0.00002226444,0.00005328147,0.00003397001],"domain_scores_gemma":[0.9998647,0.00002924081,0.00003419464,0.00001452491,0.00001434801,0.0000430622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003164951,0.0000151642,0.0003244912,0.000006194497,0.000003687513,0.00009040371,0.000008942144,0.0000266552,0.999016,0.00006138795,0.00001587101,0.0003994427],"study_design_scores_gemma":[0.00001250992,0.00008168202,0.009980046,0.000006021588,0.00001468065,0.0008059358,0.00004868909,0.001164287,0.9870236,0.00006076086,0.0007952849,0.00000657721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985857,0.0001023306,0.0006514887,0.00004501325,0.000004195826,0.000005419591,0.0001162349,0.00001574478,0.0004738588],"genre_scores_gemma":[0.9976507,0.00008033452,0.000910407,0.00002584511,0.000002868156,0.000009374727,0.0004352618,0.00002541653,0.0008598046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001260984,"threshold_uncertainty_score":0.003576279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006694037345538294,"score_gpt":0.2224999034271124,"score_spread":0.2158058660815741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}