{"id":"W2120489546","doi":"10.1093/schbul/sbt090","title":"Effects of Risperidone and Olanzapine Dose Reduction on Cognitive Function in Stable Patients With Schizophrenia: An Open-Label, Randomized, Controlled, Pilot Study","year":2013,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Mitsubishi Tanabe Pharma Corporation; Astellas Foundation for Research on Metabolic Disorders; Otsuka Pharmaceutical; Shionogi; Astellas Pharma; Kanae Foundation for the Promotion of Medical Science; Kyowa Hakko Kirin; Gedeon Richter; National Institute of Mental Health; Meiji Seika Pharma; Pfizer; Dainippon Sumitomo Pharma; GlaxoSmithKline; Government of Canada; Pfizer Japan; Abbott Laboratories; Medicure; Eli Lilly and Company; Japanese Society of Clinical Neuropsychopharmacology; Indiana Clinical and Translational Sciences Institute; Eisai","keywords":"Olanzapine; Risperidone; Extrapyramidal symptoms; Positive and Negative Syndrome Scale; Schizophrenia (object-oriented programming); Repeatable Battery for the Assessment of Neuropsychological Status; Antipsychotic; Internal medicine; Randomized controlled trial; Cambridge Neuropsychological Test Automated Battery; Typical antipsychotic; Psychology; Atypical antipsychotic; Medicine; Psychiatry; Cognition; Neuropsychology; Psychosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002624124,0.001540949,0.003068308,0.000625465,0.0004721243,0.0007955123,0.0009572196,0.0015616,0.003166894],"category_scores_gemma":[0.002853523,0.0008175814,0.001987096,0.0004846585,0.001359108,0.0009618267,0.0004197409,0.002223964,0.0005613145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006437574,"about_ca_system_score_gemma":0.001220217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001472055,"about_ca_topic_score_gemma":0.003219851,"domain_scores_codex":[0.9984238,0.0009236221,0.0001750684,0.0001640643,0.000147873,0.0001655786],"domain_scores_gemma":[0.9976234,0.0008960073,0.0004851011,0.0002213999,0.0001945306,0.0005795511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9540172,0.02234121,0.0009134723,0.0003714535,0.0006366892,0.00005989452,0.00008891805,0.0002074794,0.005251637,0.00003289256,0.000246817,0.01583246],"study_design_scores_gemma":[0.7520909,0.2431499,0.0032287,0.00001258633,0.0003232278,0.0000311717,0.00002876828,0.0003540447,0.0005567343,0.00004136746,0.0001635876,0.00001905902],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996449,0.0009276191,0.0002830687,0.0001406985,0.0001490007,0.001342959,0.0002690843,0.00005799582,0.0003805997],"genre_scores_gemma":[0.9941134,0.0009935929,0.001375437,0.0003390456,0.0002891486,0.001811374,0.0003631842,0.00001564015,0.0006991716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003166894,"threshold_uncertainty_score":0.01387787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01439224461601364,"score_gpt":0.2654330148045577,"score_spread":0.251040770188544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}