{"id":"W2120489546","doi":"10.1093/schbul/sbt090","title":"Effects of Risperidone and Olanzapine Dose Reduction on Cognitive Function in Stable Patients With Schizophrenia: An Open-Label, Randomized, Controlled, Pilot Study","year":2013,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Mitsubishi Tanabe Pharma Corporation; Astellas Foundation for Research on Metabolic Disorders; Otsuka Pharmaceutical; Shionogi; Astellas Pharma; Kanae Foundation for the Promotion of Medical Science; Kyowa Hakko Kirin; Gedeon Richter; National Institute of Mental Health; Meiji Seika Pharma; Pfizer; Dainippon Sumitomo Pharma; GlaxoSmithKline; Government of Canada; Pfizer Japan; Abbott Laboratories; Medicure; Eli Lilly and Company; Japanese Society of Clinical Neuropsychopharmacology; Indiana Clinical and Translational Sciences Institute; Eisai","keywords":"Olanzapine; Risperidone; Extrapyramidal symptoms; Positive and Negative Syndrome Scale; Schizophrenia (object-oriented programming); Repeatable Battery for the Assessment of Neuropsychological Status; Antipsychotic; Internal medicine; Randomized controlled trial; Cambridge Neuropsychological Test Automated Battery; Typical antipsychotic; Psychology; Atypical antipsychotic; Medicine; Psychiatry; Cognition; Neuropsychology; Psychosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001029128,0.000598153,0.002309878,0.0006221402,0.0002002616,0.0001755299,0.0002057011,0.0001088329,0.0004853869],"category_scores_gemma":[0.0007821725,0.0003928508,0.00006974672,0.0005030807,0.0003257887,0.0003248986,0.0001717145,0.00059954,0.0001745632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001170319,"about_ca_system_score_gemma":0.0002227358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002017644,"about_ca_topic_score_gemma":0.0002482475,"domain_scores_codex":[0.9955295,0.001113007,0.0008907982,0.0009680323,0.0009022201,0.000596456],"domain_scores_gemma":[0.9972049,0.0008234865,0.0004000026,0.0004996141,0.0005959325,0.0004760698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9641368,0.02074439,0.003468862,0.0001417054,0.001089985,0.0000533492,0.0001328099,0.000003527805,0.0009803349,0.0002338002,0.0001689013,0.008845563],"study_design_scores_gemma":[0.7894236,0.04750419,0.1601114,0.0006243968,0.0008904508,0.00001342447,0.0002101375,0.00006481453,0.0005482373,0.0002905478,0.000005586691,0.0003132507],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762064,0.0008604083,0.0000209777,0.0004718274,0.0001578388,0.02194533,0.00002025812,0.0000734007,0.0002435026],"genre_scores_gemma":[0.9934075,0.0001557029,0.001745492,0.00008558945,0.0001321277,0.003983003,0.0001268573,0.00008408435,0.0002796481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1747132,"threshold_uncertainty_score":0.9998524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01439224461601364,"score_gpt":0.2654330148045577,"score_spread":0.251040770188544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}