{"id":"W2120494583","doi":"10.1101/gr.095224.109","title":"Population genomics in a disease targeted primary cell model","year":2009,"lang":"en","type":"article","venue":"Genome Research","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; McGill University; McGill University and Génome Québec Innovation Centre","funders":"Canadian Institutes of Health Research; Uppsala Universitet; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Biology; Genomics; Population genomics; Disease; Population; Genetics; Computational biology; Evolutionary biology; Genome; Demography; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009874674,0.00009208262,0.0001353186,0.0001384665,0.00009836832,0.000014567,0.0001921915,0.0001347733,0.00001006089],"category_scores_gemma":[0.0001384871,0.00009621296,0.00005338643,0.000179818,0.00003149185,0.000002689507,0.00009262939,0.0001716004,0.00002405541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001295249,"about_ca_system_score_gemma":0.0002036824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000040078,"about_ca_topic_score_gemma":0.00002179918,"domain_scores_codex":[0.9985906,0.0002110619,0.0002237017,0.00033934,0.0001659531,0.0004693824],"domain_scores_gemma":[0.9993849,0.00001760089,0.00003923851,0.000323405,0.00009321532,0.0001416394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002486508,0.0003479342,0.1132331,0.00003396259,0.00001471249,0.000009880392,0.0001933992,0.07946379,0.8009531,0.0001738762,0.001484523,0.003843021],"study_design_scores_gemma":[0.0003871218,0.0001318833,0.9841465,0.000002427742,0.000003213302,5.076531e-7,0.00002501373,0.008122758,0.0003011067,0.004205699,0.002528647,0.0001450723],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994413,0.001595041,0.001287853,0.0006295063,0.00001814371,0.0002622363,0.00002348333,0.000006343405,0.001764366],"genre_scores_gemma":[0.994195,0.0005427815,0.003118999,0.0002829472,0.0001102477,0.00002303311,0.0006127396,0.00001248882,0.001101711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8709134,"threshold_uncertainty_score":0.392345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03581844308125943,"score_gpt":0.3302875618994994,"score_spread":0.2944691188182399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}