{"id":"W2120629149","doi":"10.3109/10428194.2012.737917","title":"A phase I/II study of sorafenib in combination with low dose cytarabine in elderly patients with acute myeloid leukemia or high-risk myelodysplastic syndrome from the National Cancer Institute of Canada Clinical Trials Group: trial IND.186","year":2012,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; Princess Margaret Cancer Centre; University Health Network; McGill University; Jewish General Hospital; Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Medicine; Cytarabine; Internal medicine; Sorafenib; Myeloid leukemia; Myelodysplastic syndromes; Oncology; Rash; Cancer; Leukemia; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001153272,0.001292734,0.001460512,0.0003971375,0.0003819364,0.0006240841,0.0005650667,0.0008230064,0.003582709],"category_scores_gemma":[0.0006360336,0.0004656134,0.0009360044,0.0003804131,0.0006780722,0.0004238716,0.0002491391,0.001821931,0.0006767284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007674905,"about_ca_system_score_gemma":0.001775441,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001988609,"about_ca_topic_score_gemma":0.005582683,"domain_scores_codex":[0.9997411,0.0001212694,0.00001385566,0.00003794209,0.00002418838,0.00006159178],"domain_scores_gemma":[0.9995951,0.00004568961,0.00005984677,0.00002188172,0.00002633528,0.0002511407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.854269,0.04537487,0.005594632,0.0008093768,0.001018775,0.0003493195,0.0002174602,0.001496322,0.02695986,0.0002896003,0.005659988,0.05796079],"study_design_scores_gemma":[0.8353314,0.1528033,0.007538626,0.00001978989,0.0002009842,0.00013293,0.00003337861,0.0005976409,0.001059734,0.00008910264,0.002175205,0.00001791351],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917944,0.002202655,0.000338958,0.000524478,0.0001135561,0.002654308,0.001018991,0.00004888819,0.00130372],"genre_scores_gemma":[0.9860966,0.002577306,0.001562824,0.0009091656,0.0001850735,0.003239375,0.002116312,0.00001948692,0.003293953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9980114,"threshold_uncertainty_score":0.01198536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03020316122113193,"score_gpt":0.3264832382603513,"score_spread":0.2962800770392194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}