{"id":"W2120642008","doi":"10.1093/annonc/mdl056","title":"Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada – Clinical Trials Group (NCIC-CTG)","year":2006,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; Hôpital Notre-Dame; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Metastatic breast cancer; Temozolomide; Oncology; Clinical trial; Breast cancer; Internal medicine; Cancer; Gynecology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009331857,0.0008371833,0.001350548,0.0003035421,0.0003622218,0.0004874039,0.0005111059,0.0006918951,0.002880795],"category_scores_gemma":[0.0007920431,0.0002269931,0.0006070776,0.0004634064,0.0005478087,0.0003682818,0.0002269592,0.002072627,0.0003629963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001582076,"about_ca_system_score_gemma":0.002481895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0150313,"about_ca_topic_score_gemma":0.0646216,"domain_scores_codex":[0.999828,0.00007827235,0.000005980909,0.00002165986,0.00002227639,0.00004377248],"domain_scores_gemma":[0.9996196,0.00006076683,0.0000540326,0.00001697519,0.00002445921,0.0002242596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6776758,0.01801819,0.007144152,0.001939937,0.001912533,0.0002410227,0.00029048,0.002886154,0.01664951,0.0008486985,0.02322865,0.2491648],"study_design_scores_gemma":[0.8413663,0.1208731,0.02373533,0.00009990403,0.0009892749,0.000325603,0.00009718472,0.001165999,0.002001114,0.0003082612,0.009008645,0.00002922699],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811842,0.01036813,0.0002698592,0.001947349,0.0001980246,0.001187212,0.001547384,0.00006393369,0.003234004],"genre_scores_gemma":[0.9761213,0.01214378,0.001788175,0.001473357,0.000208701,0.001113937,0.002727375,0.00002865984,0.004394678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0150313,"threshold_uncertainty_score":0.02988762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2658599610808156,"score_gpt":0.5287769800145659,"score_spread":0.2629170189337503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}