{"id":"W2120672148","doi":"10.1093/annonc/mdh064","title":"The effect of exemestane on serum lipid profile in postmenopausal women with metastatic breast cancer: a companion study to EORTC Trial 10951, ‘Randomized phase II study in first line hormonal treatment for metastatic breast cancer with exemestane or tamoxifen in postmenopausal patients’","year":2004,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Exemestane; Oncology; Internal medicine; Cancer; Metastatic breast cancer; Breast cancer; Randomized controlled trial; Menopause; Postmenopausal women; Hormonal therapy; Hormone; Aromatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001365794,0.0005099559,0.001638619,0.0002578665,0.0001095506,0.00001353119,0.0002438945,0.000102074,0.00001280281],"category_scores_gemma":[0.00008255793,0.0002694195,0.00008164602,0.0005084917,0.0001830656,0.00001777721,0.00008681072,0.000193271,5.697257e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003380902,"about_ca_system_score_gemma":0.0007268856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001981554,"about_ca_topic_score_gemma":0.01080122,"domain_scores_codex":[0.9964291,0.0009636082,0.0009636622,0.0006246581,0.000339249,0.0006796879],"domain_scores_gemma":[0.9983016,0.000444219,0.0005154781,0.0003485319,0.00022305,0.0001671635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9348029,0.03333055,0.006112853,0.00007384396,0.001632203,0.000165551,0.002482661,0.0026889,0.002616195,0.000004848737,0.00001766211,0.01607187],"study_design_scores_gemma":[0.5177536,0.4668519,0.01034936,0.0001288346,0.0003434599,0.00003337408,0.0007785772,0.00003776566,0.003433013,0.000005664974,0.00003344894,0.0002510667],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834549,0.0002939432,0.000005348076,0.0007363615,0.00009752864,0.01477114,0.0006200873,0.000007688815,0.00001300095],"genre_scores_gemma":[0.9928359,0.000292375,0.00008366093,0.0000795162,0.00005537206,0.006452402,0.0001140338,0.00005196187,0.00003475765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4335213,"threshold_uncertainty_score":0.9999758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054533056351236,"score_gpt":0.3526353880587899,"score_spread":0.3320900574952775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}