{"id":"W2120686108","doi":"10.1128/aac.00565-13","title":"Antiviral Effect, Safety, and Pharmacokinetics of Five-Day Oral Administration of Deleobuvir (BI 207127), an Investigational Hepatitis C Virus RNA Polymerase Inhibitor, in Patients with Chronic Hepatitis C","year":2013,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Hepatitis C virus research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Cirrhosis; Hepatitis C virus; NS5B; Medicine; Gastroenterology; Pharmacokinetics; Internal medicine; Hepatitis C; Adverse effect; Placebo; Hepacivirus; Virus; Pharmacology; Immunology; Virology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007848481,0.0003949111,0.0006785596,0.0001698718,0.0002545315,0.0003300763,0.0002017674,0.0004489813,0.0005439044],"category_scores_gemma":[0.001390964,0.0002812044,0.0003779244,0.0001535516,0.0003935504,0.0004114043,0.0001433126,0.0008303544,0.0001670609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003251139,"about_ca_system_score_gemma":0.0003264927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005530324,"about_ca_topic_score_gemma":0.000692089,"domain_scores_codex":[0.9995978,0.0002090822,0.00002395337,0.00005290577,0.00006196713,0.00005432562],"domain_scores_gemma":[0.9994343,0.0001793955,0.0001388281,0.00003696097,0.00003475548,0.0001757326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.315625,0.02747431,0.06831988,0.0005922258,0.0007135504,0.0007766605,0.00119518,0.00470686,0.2334541,0.0002832688,0.001812901,0.3450461],"study_design_scores_gemma":[0.03890451,0.6843231,0.2432909,0.00004729316,0.00036841,0.00113122,0.0002042325,0.005934978,0.02343857,0.0001629475,0.002102925,0.00009096273],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991736,0.0003729864,0.0001069603,0.00002665981,0.000006215127,0.00004479015,0.0000452015,0.00001238024,0.0002112736],"genre_scores_gemma":[0.9993258,0.0001228686,0.0002148138,0.00004601615,0.00001492479,0.00003549781,0.00009397478,0.000002834782,0.000143447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007848481,"threshold_uncertainty_score":0.004150689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008401042019181428,"score_gpt":0.2659090119823583,"score_spread":0.2575079699631769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}