{"id":"W2120692021","doi":"10.1128/iai.00446-08","title":"<i>Escherichia coli</i>O157:H7 Survives within Human Macrophages: Global Gene Expression Profile and Involvement of the Shiga Toxins","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; Biotechnology Research Institute; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Shiga toxin; Microbiology; Escherichia coli; Virulence; Gene; Pathogen; Operon; Enterobacteriaceae; Downregulation and upregulation; Mutant; Human pathogen; Macrophage; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000207562,0.000116997,0.000123137,0.00001408033,0.0005126465,0.00001434023,0.00008900101,0.00007920548,0.000008805066],"category_scores_gemma":[0.00008847396,0.00008577845,0.00004184404,0.0001197427,0.0003572374,0.000008204986,0.0003881268,0.0001326413,4.700733e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001592537,"about_ca_system_score_gemma":0.00005089558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007062068,"about_ca_topic_score_gemma":0.0003518645,"domain_scores_codex":[0.9991857,0.0002323448,0.0001592507,0.0001653009,0.0001224962,0.0001349452],"domain_scores_gemma":[0.9995103,0.00001022796,0.00009023233,0.0002437442,0.00009557806,0.00004991116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003339297,0.00009413785,0.1676278,0.00003275804,0.00003446649,3.808138e-7,0.0002366738,0.000003563336,0.8316222,0.00002433805,0.0002196003,0.00007075628],"study_design_scores_gemma":[0.0003827664,0.0002299573,0.4568987,0.0000165734,0.000006754941,0.000005432743,0.0001261874,0.00001224969,0.5412698,0.00002706719,0.0009446518,0.00007989566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978776,0.0008056316,0.00007204151,0.0000317131,0.00008732564,0.000246179,0.00002027452,0.00001063759,0.0008485903],"genre_scores_gemma":[0.9982188,0.001160621,0.0002082374,0.0000925917,0.00003718115,0.00002090505,0.00001501845,0.000006886016,0.000239756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2903524,"threshold_uncertainty_score":0.3942914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02163365918183101,"score_gpt":0.2766216348997924,"score_spread":0.2549879757179614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}