{"id":"W2120718521","doi":"10.1038/msb.2010.79","title":"Intra‐ and inter‐chromosomal interactions correlate with CTCF binding genome wide","year":2010,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Agence Nationale de la Recherche; European Commission","keywords":"CTCF; Biology; Genome; Chromosome conformation capture; Chromatin; Genetics; Cohesin; Chromatin immunoprecipitation; Chromosome; Replication timing; Computational biology; ChIA-PET; DNA; Gene; Transcription factor; Chromatin remodeling; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001449683,0.000235575,0.0002364502,0.0000848213,0.0001086129,0.00006104722,0.0002111111,0.0002498311,0.00001447242],"category_scores_gemma":[0.00004262526,0.0002032128,0.00005859949,0.00007461087,0.0001851614,0.000004635378,0.0001758408,0.0002804112,0.00001985234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001584338,"about_ca_system_score_gemma":0.00005112704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005576819,"about_ca_topic_score_gemma":0.0001732703,"domain_scores_codex":[0.9987963,0.00007831621,0.0002757599,0.0004738394,0.00005132253,0.000324398],"domain_scores_gemma":[0.9992157,0.00001653695,0.0001489862,0.0004201818,0.00007578232,0.0001228083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003055318,0.00002526248,0.007310437,0.00002216273,0.0001268923,0.00002328806,0.00004278027,0.00006528676,0.9911056,0.0008724972,0.000038953,0.0003363378],"study_design_scores_gemma":[0.01065412,0.008561939,0.044446,0.0004359535,0.0007159545,0.01647975,0.002117193,0.02500529,0.3618456,0.0008142457,0.5222646,0.006659388],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809902,0.0003097116,0.01651791,0.0001028791,0.0007832697,0.0002584804,0.00004149977,0.00002351585,0.0009725193],"genre_scores_gemma":[0.9980991,0.00003614254,0.0009045037,0.0001166706,0.0001411234,0.00004457641,0.0002803274,0.00004285593,0.0003346779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6292599,"threshold_uncertainty_score":0.8286778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003391687246885604,"score_gpt":0.2069478093516803,"score_spread":0.2035561221047947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}