{"id":"W2120718521","doi":"10.1038/msb.2010.79","title":"Intra‐ and inter‐chromosomal interactions correlate with CTCF binding genome wide","year":2010,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Agence Nationale de la Recherche; European Commission","keywords":"CTCF; Biology; Genome; Chromosome conformation capture; Chromatin; Genetics; Cohesin; Chromatin immunoprecipitation; Chromosome; Replication timing; Computational biology; ChIA-PET; DNA; Gene; Transcription factor; Chromatin remodeling; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004180284,0.0001686756,0.0004280564,0.001255435,0.0003467948,0.001118359,0.0002863292,0.0004271584,0.002618978],"category_scores_gemma":[0.001841734,0.0002930561,0.0002474387,0.001040102,0.0004082787,0.0003845821,0.0006396967,0.0008993783,0.0008725829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003201099,"about_ca_system_score_gemma":0.0001826073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002416142,"about_ca_topic_score_gemma":0.005070165,"domain_scores_codex":[0.9992055,0.00004936006,0.00002770742,0.0002882052,0.0002222128,0.0002068754],"domain_scores_gemma":[0.9979248,0.000840235,0.0004129739,0.0002531818,0.0002620645,0.0003067183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002926423,0.0001023095,0.187227,0.00009171746,0.0002251891,0.0001250659,0.0001566956,0.0007070901,0.7941174,0.0003873185,0.0006455478,0.01592201],"study_design_scores_gemma":[0.000007908476,0.00003996022,0.9567932,0.00000333675,0.00004391724,0.0002496421,0.00006887316,0.001244637,0.03991961,0.0002338587,0.001380029,0.00001502458],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889658,0.001628199,0.005043905,0.000102342,0.00001133482,0.00001034381,0.001007923,0.0001663744,0.003063748],"genre_scores_gemma":[0.9959577,0.00019517,0.0009169487,0.00005863956,0.000008381226,0.00001615812,0.001917272,0.00003841985,0.0008912308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002618978,"threshold_uncertainty_score":0.008761346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003391687246885604,"score_gpt":0.2069478093516803,"score_spread":0.2035561221047947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}