{"id":"W2120809213","doi":"10.1016/j.pep.2013.04.004","title":"Expression, purification and preliminary characterization of glucagon receptor extracellular domain","year":2013,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Glucagon receptor; Fusion protein; G protein-coupled receptor; Biochemistry; Glucagon; Receptor; Glucose homeostasis; Glucagon-like peptide 1 receptor; Biology; Chemistry; Endocrinology; Agonist; Recombinant DNA; Insulin; Hormone; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005382402,0.0004578734,0.000406955,0.0003464039,0.0005201361,0.0004975582,0.0004474238,0.0002962925,0.0008935248],"category_scores_gemma":[0.0005777596,0.0003204452,0.0005218352,0.0007559922,0.0002906235,0.0003924593,0.0004607256,0.001326801,0.001079939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004470503,"about_ca_system_score_gemma":0.0004292522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001591864,"about_ca_topic_score_gemma":0.0017165,"domain_scores_codex":[0.9996864,0.00005793072,0.00003944598,0.00005247353,0.00007759694,0.00008619674],"domain_scores_gemma":[0.9997463,0.00007946959,0.00002442429,0.00005068999,0.00005527697,0.0000438946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001612247,0.00007164625,0.0002873119,0.00008535542,0.000009541398,0.0001774463,0.00008311047,0.0001840311,0.9959287,0.0004970851,0.0002512593,0.002263337],"study_design_scores_gemma":[0.0000385515,0.0001219117,0.006013518,0.0000142645,0.00002833318,0.0007612518,0.00009283599,0.001532279,0.972349,0.0003819096,0.01864658,0.00001953937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8997917,0.005124971,0.07993508,0.001550141,0.0002177536,0.000554908,0.008565527,0.0002866297,0.003973335],"genre_scores_gemma":[0.8138782,0.00538439,0.1175129,0.000593329,0.0001198353,0.0006829019,0.04468112,0.0002429539,0.01690442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001591864,"threshold_uncertainty_score":0.003243566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007601106293689376,"score_gpt":0.2090166156472713,"score_spread":0.2014155093535819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}