{"id":"W2120809213","doi":"10.1016/j.pep.2013.04.004","title":"Expression, purification and preliminary characterization of glucagon receptor extracellular domain","year":2013,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Glucagon receptor; Fusion protein; G protein-coupled receptor; Biochemistry; Glucagon; Receptor; Glucose homeostasis; Glucagon-like peptide 1 receptor; Biology; Chemistry; Endocrinology; Agonist; Recombinant DNA; Insulin; Hormone; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466336,0.0001505976,0.0001330517,0.00005965458,0.0001286621,0.00004587609,0.00009853746,0.0002050768,0.0001960618],"category_scores_gemma":[0.00005067346,0.000131666,0.0000307437,0.00006240837,0.00005820398,0.00003683522,0.00005633584,0.00007252618,0.000008532924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005285487,"about_ca_system_score_gemma":0.00001731168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006694941,"about_ca_topic_score_gemma":9.425786e-8,"domain_scores_codex":[0.9988688,0.0001335224,0.0003257841,0.000386844,0.000145991,0.0001390221],"domain_scores_gemma":[0.9992145,0.000008716799,0.0002614679,0.0002886101,0.0001317285,0.00009499717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008281456,0.00005902323,0.000119468,0.00006829573,0.000004315527,5.97681e-8,0.0002247407,8.799357e-7,0.9876741,0.0002440677,0.0001065781,0.01141571],"study_design_scores_gemma":[0.0003013886,0.0001713273,0.001772532,0.0001206025,0.000004586161,0.000002175839,0.0001764753,0.0001084406,0.990585,0.000444079,0.006158689,0.0001547253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9614956,0.001212194,0.03601651,0.0002059303,0.00005575118,0.0009309287,0.000009800316,0.00001720301,0.00005608963],"genre_scores_gemma":[0.9847933,0.0004589522,0.01312006,0.00002031178,0.0001034269,0.0003908931,0.0004061886,0.00002238175,0.0006844668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02329773,"threshold_uncertainty_score":0.5369182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007601106293689376,"score_gpt":0.2090166156472713,"score_spread":0.2014155093535819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}