{"id":"W2120842530","doi":"10.1016/j.bone.2014.02.003","title":"Cells of origin in osteosarcoma: Mesenchymal stem cells or osteoblast committed cells?","year":2014,"lang":"en","type":"review","venue":"Bone","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"OVC Pet Trust; Cancer Council Victoria","keywords":"Osteosarcoma; Mesenchymal stem cell; Osteoblast; Osteoid; Population; Cancer research; Cell; Biology; Stem cell; Disease; Pathology; Cell biology; Medicine; Immunology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004683383,0.0008653563,0.004949459,0.0005703079,0.00004593751,0.00002814306,0.0003123831,0.0005776149,0.0004681222],"category_scores_gemma":[0.00001754932,0.0005829009,0.0008928769,0.0007541471,0.0001288078,0.0000471169,0.0001782665,0.0006085577,0.0009482166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003460865,"about_ca_system_score_gemma":0.0004943526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000208928,"about_ca_topic_score_gemma":0.0001423018,"domain_scores_codex":[0.995833,0.0003915047,0.001741071,0.0007725721,0.0006080884,0.0006538021],"domain_scores_gemma":[0.9965944,0.0009424015,0.0008265274,0.001211754,0.000109455,0.0003154757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001816568,0.003011148,0.0005320738,0.04043296,0.00059486,0.002373151,0.0001420059,0.000001272664,0.0002214208,0.00007691474,0.01110275,0.9413298],"study_design_scores_gemma":[0.003152362,0.0006938033,0.00006748532,0.02116408,0.001990825,0.0001669563,0.00005931986,0.000007060927,0.002713829,0.000002526304,0.9694799,0.000501889],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002962193,0.9918648,0.000003799788,0.00007129584,0.0006049527,0.002756234,0.0002230088,0.00005867487,0.001455051],"genre_scores_gemma":[0.002322245,0.99193,0.0005243768,0.00008623214,0.0002501613,0.0003057304,0.0001330819,0.0001607182,0.004287468],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9583771,"threshold_uncertainty_score":0.9998296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06089811689398601,"score_gpt":0.3318851935358837,"score_spread":0.2709870766418978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}