{"id":"W2120845130","doi":"10.1006/dbio.2002.0781","title":"SEK1/MKK4-Mediated SAPK/JNK Signaling Participates in Embryonic Hepatoblast Proliferation via a Pathway Different from NF-κB-Induced Anti-Apoptosis","year":2002,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Liver physiology and pathology","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":false,"ca_institutions":"Amgen (Canada); University of Toronto; Ontario Institute for Cancer Research","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Biology; Embryonic stem cell; Apoptosis; Hepatocyte; Cell biology; Hepatocyte growth factor; Embryogenesis; Embryo; Signal transduction; Kinase; Cancer research; Receptor; Gene; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003675643,0.0006580424,0.0003357723,0.0004692826,0.0003397035,0.0005157687,0.0003211897,0.0002800184,0.00192943],"category_scores_gemma":[0.0002491361,0.0003650396,0.0004327988,0.0001974514,0.0003775546,0.0006708944,0.0005115014,0.0007970656,0.0006107026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004651947,"about_ca_system_score_gemma":0.0003864438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002874454,"about_ca_topic_score_gemma":0.0003993659,"domain_scores_codex":[0.9997552,0.00005446761,0.0000314872,0.00003994569,0.0000576551,0.00006118266],"domain_scores_gemma":[0.9997937,0.00002102636,0.00006806202,0.00003186208,0.00003298384,0.00005237671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005311447,0.0000220073,0.00134189,0.000201918,0.00002232944,0.0003356986,0.00005560202,0.0001324329,0.9922651,0.0008171889,0.000100137,0.004174547],"study_design_scores_gemma":[0.00003973213,0.0001521518,0.0174654,0.00001029177,0.00004211275,0.001388923,0.00009165888,0.0008312208,0.9759589,0.0002924091,0.003717379,0.000009768093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838134,0.003876964,0.008206282,0.0002108761,0.00006700282,0.0000280132,0.0004373577,0.0001843429,0.003175842],"genre_scores_gemma":[0.989058,0.001255604,0.005160351,0.00005381292,0.00002015323,0.00004224062,0.0005499707,0.00002720498,0.003832593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00192943,"threshold_uncertainty_score":0.006454587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04010604246229843,"score_gpt":0.2514963250008778,"score_spread":0.2113902825385794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}