{"id":"W2120846842","doi":"10.1111/j.1751-7915.2011.00267.x","title":"Directed evolution, natural products for cancer chemotherapy, and micro‐biosensing robots","year":2011,"lang":"en","type":"article","venue":"Microbial Biotechnology","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Computational biology; Synthetic biology; Bacillus subtilis; Biology; Escherichia coli; Plasmid; Restriction enzyme; Cloning (programming); Gene; Biotechnology; Genetics; Computer science; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003774169,0.000389504,0.0004206634,0.0005852058,0.0002066694,0.0006210275,0.0005684071,0.0007670168,0.001597716],"category_scores_gemma":[0.0003529748,0.0002611019,0.0004500669,0.0005835912,0.0006069876,0.0005955787,0.0005988817,0.00124975,0.001090202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005660483,"about_ca_system_score_gemma":0.0002176758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004404559,"about_ca_topic_score_gemma":0.0005105865,"domain_scores_codex":[0.999667,0.0000620841,0.00001603763,0.00007527366,0.0001553217,0.00002417752],"domain_scores_gemma":[0.9998677,0.00003848448,0.00003964081,0.00001436733,0.00002249595,0.0000172809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002180186,0.0002120018,0.0006228492,0.002153437,0.00008855393,0.0003702712,0.0001637648,0.003426257,0.660356,0.04408181,0.009242213,0.2790647],"study_design_scores_gemma":[0.000112082,0.0008954738,0.001766377,0.0002004316,0.00007972171,0.001885186,0.00006434996,0.008071367,0.5011117,0.0180255,0.4676954,0.00009223765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1065589,0.4300784,0.3890024,0.006178451,0.002617274,0.0005017135,0.0008250082,0.002490577,0.06174712],"genre_scores_gemma":[0.4677228,0.1709179,0.3087451,0.004817247,0.0006845089,0.0007784776,0.001297231,0.000414711,0.04462213],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001597716,"threshold_uncertainty_score":0.005344868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208250319814504,"score_gpt":0.2502405326686015,"score_spread":0.2381580294704565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}