{"id":"W2120879362","doi":"10.1093/carcin/bgh103","title":"Cytokine production by alveolar macrophages is down regulated by the  -methylhydroxylation pathway of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)","year":2004,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Cytokine; Carcinogen; Tumor necrosis factor alpha; Nitric oxide; Biochemistry; Endocrinology; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002336566,0.0003837133,0.0003892397,0.0001597423,0.000156082,0.0002328679,0.0001142327,0.0002619292,0.0008310727],"category_scores_gemma":[0.0001402376,0.0001571108,0.0003396902,0.0001086719,0.0002478193,0.0002116483,0.0002297018,0.0005179381,0.0004409678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001191133,"about_ca_system_score_gemma":0.0001500265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001607942,"about_ca_topic_score_gemma":0.0002806995,"domain_scores_codex":[0.9997199,0.0000757141,0.00003198516,0.00003925247,0.00004946244,0.00008367529],"domain_scores_gemma":[0.9998748,0.00002188129,0.00003283461,0.00001671086,0.00002301333,0.0000308295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003892806,0.00005336077,0.0003895335,0.00004145541,0.000003291397,0.0001077005,0.00002314532,0.00002022908,0.9978781,0.00002213385,0.00001910089,0.001052705],"study_design_scores_gemma":[0.00009536537,0.002096298,0.02088656,0.00001748528,0.00003777575,0.0005620566,0.0001166141,0.0005847843,0.9732183,0.00007481332,0.002301936,0.000008054634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928178,0.004044279,0.00134203,0.0001219041,0.00007207303,0.00004429268,0.0001698343,0.00004032172,0.001347626],"genre_scores_gemma":[0.9950959,0.00177893,0.001224871,0.00008931472,0.00005899706,0.00009548747,0.0002048953,0.000007731487,0.001443884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008310727,"threshold_uncertainty_score":0.002780199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007870687670618501,"score_gpt":0.2311133466669784,"score_spread":0.2232426589963599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}