{"id":"W2120905326","doi":"10.1128/aac.01072-08","title":"MexCD-OprJ Multidrug Efflux System of <i>Pseudomonas aeruginosa</i> : Involvement in Chlorhexidine Resistance and Induction by Membrane-Damaging Agents Dependent upon the AlgU Stress Response Sigma Factor","year":2008,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Efflux; Sigma factor; Pseudomonas aeruginosa; Operon; Mutant; Biology; Microbiology; Cell biology; Gene expression; Gene; Biochemistry; Bacteria; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006939917,0.0002308538,0.0001802408,0.0001694261,0.0001175569,0.0002614008,0.0001141472,0.0001290963,0.000617013],"category_scores_gemma":[0.0001322469,0.0001166305,0.0001274679,0.0001106722,0.0001718646,0.000118186,0.0002006402,0.0002746719,0.0002215714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003263135,"about_ca_system_score_gemma":0.0002002243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001617438,"about_ca_topic_score_gemma":0.001631144,"domain_scores_codex":[0.9998887,0.00001375049,0.00001073331,0.00001756505,0.00004244317,0.0000268787],"domain_scores_gemma":[0.9998789,0.00001753693,0.00003836348,0.00001792855,0.00002098181,0.00002632354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001420481,0.00000330288,0.0001032323,0.00000610946,5.558884e-7,0.00001483173,0.000005315564,0.000005831122,0.9996018,0.00001560519,0.000005761253,0.0002235096],"study_design_scores_gemma":[0.000003255342,0.00006337051,0.01320784,0.000002934487,0.000005606336,0.0003443927,0.00004234139,0.0002798519,0.9854327,0.00002121086,0.0005910027,0.000005402679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980972,0.0002496694,0.0008546475,0.00005035825,0.000004844982,0.000008620277,0.0001886164,0.00003627334,0.0005097251],"genre_scores_gemma":[0.9970606,0.0001654999,0.00106525,0.00001956314,0.000003507936,0.0000142471,0.0006151287,0.00001805649,0.001038017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001617438,"threshold_uncertainty_score":0.003216028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077111721849178,"score_gpt":0.2291696427859855,"score_spread":0.2183985255674937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}