{"id":"W2120957859","doi":"10.4049/jimmunol.1103136","title":"NLRC5 Controls Basal MHC Class I Gene Expression in an MHC Enhanceosome-Dependent Manner","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"MHC class I; Biology; CD74; Transactivation; MHC class II; Major histocompatibility complex; MHC restriction; C-C chemokine receptor type 7; Cell biology; Transporter associated with antigen processing; Gene expression; Genetics; Immune system; Gene; Chemokine receptor; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002262238,0.0003202314,0.00023715,0.0002714306,0.0001752036,0.0004647102,0.0002753563,0.0002780015,0.001796731],"category_scores_gemma":[0.0001346575,0.0001330641,0.0003706619,0.0001297932,0.0003518208,0.000233391,0.0002306267,0.0005382719,0.0007163679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006078146,"about_ca_system_score_gemma":0.0002218054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006448461,"about_ca_topic_score_gemma":0.0009774831,"domain_scores_codex":[0.9995013,0.00008123733,0.00005760397,0.0001516203,0.00009858877,0.0001096828],"domain_scores_gemma":[0.9997965,0.00002854674,0.00007210993,0.00003620007,0.00001993536,0.0000468043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008637757,0.00001632056,0.0001204638,0.00003322909,0.000003766971,0.00002499882,0.00001234251,0.00003926836,0.9988939,0.0001150062,0.00003891516,0.0006154844],"study_design_scores_gemma":[0.00002138532,0.0001099683,0.003813768,0.000007305547,0.00001505303,0.0001424828,0.00003052397,0.001442708,0.9906617,0.00003640432,0.003713869,0.000004889249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791228,0.003699523,0.01117962,0.0001892578,0.0001242346,0.00007112767,0.0009994291,0.0004233565,0.004190618],"genre_scores_gemma":[0.9912884,0.0005358284,0.002464967,0.00008389687,0.0000147776,0.00004940356,0.0008934996,0.00005540191,0.004613866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001796731,"threshold_uncertainty_score":0.006010652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271643418582529,"score_gpt":0.2483647883937553,"score_spread":0.23564835420793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}