{"id":"W2120957859","doi":"10.4049/jimmunol.1103136","title":"NLRC5 Controls Basal MHC Class I Gene Expression in an MHC Enhanceosome-Dependent Manner","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"MHC class I; Biology; CD74; Transactivation; MHC class II; Major histocompatibility complex; MHC restriction; C-C chemokine receptor type 7; Cell biology; Transporter associated with antigen processing; Gene expression; Genetics; Immune system; Gene; Chemokine receptor; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00126693,0.0002007315,0.0004164632,0.0002558668,0.0001665702,0.00001332785,0.0004365583,0.0003378107,0.001905968],"category_scores_gemma":[0.000115326,0.0001295258,0.0001231584,0.00009649665,0.0001867175,0.0006108248,0.00009511101,0.001083887,0.0005829241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001230359,"about_ca_system_score_gemma":0.00004918912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003466338,"about_ca_topic_score_gemma":0.00001380008,"domain_scores_codex":[0.9972984,0.001271705,0.0007378011,0.0001182383,0.00006464572,0.0005092145],"domain_scores_gemma":[0.9985856,0.0002750076,0.0005894804,0.0003552038,0.0001647155,0.00002997933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002812536,0.0003842408,0.001293447,0.000002555534,0.0001435971,0.000004425693,0.001128767,0.00002851444,0.9899703,0.000100338,0.002416149,0.001715152],"study_design_scores_gemma":[0.00347528,0.0009729276,0.01925828,0.00004782629,0.0000674707,0.001172175,0.002049589,0.000004674272,0.9378461,0.00008901495,0.03483763,0.0001790277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737132,0.01441134,0.0007528013,0.0006485773,0.009538319,0.0001540718,0.000001692558,0.00002012391,0.000759906],"genre_scores_gemma":[0.9950789,0.0008411405,0.00004394811,0.0005432742,0.0002155442,0.000007015503,0.00001346089,0.00002178031,0.003234922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05212418,"threshold_uncertainty_score":0.9990065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271643418582529,"score_gpt":0.2483647883937553,"score_spread":0.23564835420793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}