{"id":"W2120998010","doi":"10.1158/1078-0432.ccr-09-1713","title":"Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer","year":2010,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":318,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Connaught Fund; University of Toronto; U.S. Department of Veterans Affairs","keywords":"Pancreatic cancer; Clonogenic assay; In vivo; Cancer research; Cancer; Viability assay; Apoptosis; Cell culture; Pharmacology; Medicine; Chemistry; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005794314,0.0006413449,0.0005579029,0.0005598163,0.000260653,0.0007467804,0.0004618462,0.0007949633,0.001333343],"category_scores_gemma":[0.0004726521,0.0001901613,0.0005024691,0.0003345489,0.0005558655,0.000560368,0.000464646,0.0005936946,0.0002701645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000695474,"about_ca_system_score_gemma":0.0002935281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001282145,"about_ca_topic_score_gemma":0.0001427719,"domain_scores_codex":[0.9996452,0.0001279915,0.00003734367,0.00006410309,0.00008438464,0.00004105368],"domain_scores_gemma":[0.9996102,0.0001102705,0.0001548709,0.00004309524,0.00005254464,0.00002890263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00171878,0.000404863,0.004381159,0.001317883,0.0001129231,0.0005572149,0.0001243918,0.001443738,0.9568192,0.001926224,0.000384181,0.03080948],"study_design_scores_gemma":[0.0001240884,0.004474042,0.01222016,0.00008775102,0.0001162451,0.002403473,0.0001174494,0.001771284,0.9691078,0.001383057,0.008178184,0.00001641668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8914782,0.07650123,0.0245431,0.001259592,0.0001705234,0.0004566551,0.0004374439,0.0004079686,0.004745279],"genre_scores_gemma":[0.9814391,0.01405199,0.002761749,0.0002402262,0.00005015922,0.0001584006,0.0002142384,0.00001311102,0.001070934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001333343,"threshold_uncertainty_score":0.00504601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2205539197400399,"score_gpt":0.5355244103895571,"score_spread":0.3149704906495172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}