{"id":"W2121005589","doi":"10.1261/rna.034785.112","title":"<i>E. coli</i> 6S RNA release from RNA polymerase requires σ<sup>70</sup> ejection by scrunching and is orchestrated by a conserved RNA hairpin","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"SFU Community Trust Endowment Fund; Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Biology; RNA polymerase; RNA; Polymerase; Transcription (linguistics); RNA-dependent RNA polymerase; Molecular biology; Small nuclear RNA; Biophysics; DNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001793248,0.0003490349,0.0003019817,0.00005626065,0.0002094252,0.00009320902,0.0002277867,0.0006933694,0.00008112378],"category_scores_gemma":[0.00007658431,0.0003427383,0.00009670939,0.0001492332,0.0002213876,0.00001991061,0.0001663621,0.0002634759,0.00001901304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002914436,"about_ca_system_score_gemma":0.0000868783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001478944,"about_ca_topic_score_gemma":0.00003541067,"domain_scores_codex":[0.9981856,0.0001331351,0.0003865257,0.0005751824,0.0001516352,0.000567873],"domain_scores_gemma":[0.9989598,0.00002363476,0.0001895041,0.0004728547,0.00006637476,0.0002878669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002295513,0.0001415826,0.0004291659,0.0000154074,0.0001073447,0.000003242561,0.00006524702,0.000001383985,0.9599103,0.00001534314,0.03303244,0.006049024],"study_design_scores_gemma":[0.000964554,0.0003205279,0.0002919142,0.00003336269,0.00006473394,0.00001325084,0.0001035662,0.0001611403,0.9503651,0.00005365017,0.04722208,0.0004060874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885988,0.008264893,0.000247346,0.001357466,0.0002395225,0.000257282,0.0005630853,0.00006162284,0.0004100191],"genre_scores_gemma":[0.9940903,0.002292354,0.0003085271,0.001474247,0.0004455441,0.00002318439,0.0007095225,0.00005227729,0.0006040501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01418964,"threshold_uncertainty_score":0.9999025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009626989725013912,"score_gpt":0.223299388159532,"score_spread":0.213672398434518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}