{"id":"W2121008130","doi":"10.1093/nar/gkl861","title":"Transcriptional regulation of the cyclin-dependent kinase inhibitor 1A (p21) gene by NFI in proliferating human cells","year":2006,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Molecular biology; Cyclin-dependent kinase; Cell cycle; Repressor; CDK inhibitor; Chromatin immunoprecipitation; Gene expression; Cell biology; Promoter; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001210737,0.0002206524,0.0001659859,0.0002864209,0.0002081387,0.0002661696,0.000107474,0.0001351121,0.0009481325],"category_scores_gemma":[0.0001553223,0.0001086874,0.0001989962,0.0001924292,0.0002374672,0.0001224823,0.0001327096,0.0002900176,0.0003948605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003318185,"about_ca_system_score_gemma":0.0002166469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094814,"about_ca_topic_score_gemma":0.0007821147,"domain_scores_codex":[0.9998879,0.00001745653,0.000009277125,0.00003521225,0.00003025532,0.00001980576],"domain_scores_gemma":[0.9999382,0.00001339364,0.0000151357,0.00000922675,0.00001181065,0.00001217469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007841401,0.00001466993,0.0002139773,0.00003080284,0.000002196888,0.00003743752,0.00002418804,0.0000277304,0.9973443,0.0001240124,0.00002719752,0.002075089],"study_design_scores_gemma":[0.00001614733,0.0002279416,0.00729106,0.000008590562,0.00001042365,0.0003061033,0.00003464163,0.0006860238,0.9847144,0.0001503943,0.006548879,0.00000526365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695439,0.01171769,0.01199585,0.0001549501,0.00008731391,0.00009163011,0.0009558373,0.0002371913,0.005215669],"genre_scores_gemma":[0.9862177,0.003346344,0.004902499,0.00003825106,0.00002421968,0.00007343568,0.0009504127,0.00002035862,0.00442676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001094814,"threshold_uncertainty_score":0.003171802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02808957624282439,"score_gpt":0.3097685771325561,"score_spread":0.2816790008897317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}