{"id":"W2121017656","doi":"10.1128/jvi.79.5.3146-3162.2005","title":"Transfer of the Full-Length Dystrophin-Coding Sequence into Muscle Cells by a Dual High-Capacity Hybrid Viral Vector with Site-Specific Integration Ability","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Leids Universitair Medisch Centrum; University of Tokyo; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Universiteit Leiden; Université Laval; Institut National de la Recherche Agronomique; University of Chicago","keywords":"Biology; Dystrophin; Duchenne muscular dystrophy; DNA; Transgene; Utrophin; Gene; Cell biology; Molecular biology; Virology; Genetics; Computational biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002711381,0.0004193486,0.0002314383,0.0002803125,0.00014243,0.0003853706,0.0002752505,0.0003850881,0.001266031],"category_scores_gemma":[0.0001210215,0.0002802099,0.0003308349,0.0001414251,0.0002931746,0.0002385099,0.000463652,0.0006123993,0.0007026065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002949335,"about_ca_system_score_gemma":0.0002377196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002432716,"about_ca_topic_score_gemma":0.0002643633,"domain_scores_codex":[0.999837,0.00002315489,0.0000171774,0.00004679817,0.00004955829,0.00002626574],"domain_scores_gemma":[0.9998846,0.0000213872,0.0000247826,0.00002057201,0.00001299386,0.00003565524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000306163,0.00001180807,0.00008569023,0.00001560807,0.000004056451,0.00002725746,0.000009962367,0.0000416779,0.9986193,0.0002162001,0.00001756723,0.0009202207],"study_design_scores_gemma":[0.00002940856,0.0003428329,0.001380364,0.000006467261,0.00003755996,0.0007813855,0.00001531941,0.00164601,0.9887017,0.00008493297,0.006964782,0.000009163142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9533818,0.0009466396,0.04241346,0.0001141816,0.00007555504,0.0001032356,0.0002941701,0.0001972924,0.002473591],"genre_scores_gemma":[0.9618226,0.0006615084,0.02851884,0.00006535731,0.00002880172,0.00008147171,0.001193074,0.00006478861,0.007563538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001266031,"threshold_uncertainty_score":0.004235327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007919003259112087,"score_gpt":0.2082144138370235,"score_spread":0.2002954105779114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}