{"id":"W2121030043","doi":"10.1016/s0166-0934(00)00240-8","title":"Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with α-fetoprotein promoter and Cre/lox P system","year":2001,"lang":"en","type":"article","venue":"Journal of Virological Methods","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"Biology; Genetic enhancement; Thymidine kinase; Hepatocellular carcinoma; Suicide gene; Recombinant DNA; Cancer research; Viral vector; Molecular biology; Gene; Reporter gene; Gene expression; Adenoviridae; Multiplicity of infection; Transduction (biophysics); Liver cancer; Virology; Virus; Herpes simplex virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006272802,0.0005220158,0.000604332,0.0005972776,0.0002831166,0.0005472653,0.0003442176,0.0006547886,0.001582621],"category_scores_gemma":[0.0002147345,0.0002734076,0.0005510041,0.0002960672,0.0003783963,0.0007309097,0.0003865293,0.001054781,0.0004598097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003618595,"about_ca_system_score_gemma":0.0005104226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004709097,"about_ca_topic_score_gemma":0.0004235784,"domain_scores_codex":[0.9997026,0.00004380558,0.00003615355,0.00006412609,0.00007749216,0.00007587419],"domain_scores_gemma":[0.9998881,0.00002243961,0.00002702349,0.00002206498,0.00001333101,0.00002701185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003571104,0.0001082829,0.0002502614,0.000113352,0.0000177148,0.0001318034,0.0000579424,0.00007668665,0.9881485,0.001399129,0.0001338064,0.009205461],"study_design_scores_gemma":[0.0001282507,0.0005617516,0.0006876003,0.000009686764,0.00006227032,0.0007700758,0.00003493208,0.0007055977,0.9899261,0.0001672158,0.006932918,0.00001351595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.871653,0.006816299,0.112683,0.0008416075,0.0007007298,0.0005160825,0.0005785348,0.0007088316,0.005501836],"genre_scores_gemma":[0.9399818,0.003011622,0.04286373,0.0001132179,0.00005088357,0.0002893097,0.0006965772,0.00006696535,0.01292589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001582621,"threshold_uncertainty_score":0.005294383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07323151288724694,"score_gpt":0.3792732107365001,"score_spread":0.3060416978492531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}