{"id":"W2121030043","doi":"10.1016/s0166-0934(00)00240-8","title":"Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with α-fetoprotein promoter and Cre/lox P system","year":2001,"lang":"en","type":"article","venue":"Journal of Virological Methods","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"Biology; Genetic enhancement; Thymidine kinase; Hepatocellular carcinoma; Suicide gene; Recombinant DNA; Cancer research; Viral vector; Molecular biology; Gene; Reporter gene; Gene expression; Adenoviridae; Multiplicity of infection; Transduction (biophysics); Liver cancer; Virology; Virus; Herpes simplex virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002530557,0.0002415515,0.0004587046,0.0001030549,0.0001372813,0.00004421863,0.00027196,0.0002140704,0.00002067342],"category_scores_gemma":[0.0001001159,0.0001511222,0.0001727867,0.0001203423,0.0001464071,0.000009592239,0.00006599304,0.0002662547,5.369027e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005209657,"about_ca_system_score_gemma":0.0001152055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001282257,"about_ca_topic_score_gemma":0.000002900779,"domain_scores_codex":[0.9976305,0.0009378049,0.0004537318,0.0003435346,0.0002350331,0.0003994135],"domain_scores_gemma":[0.9988733,0.00008473837,0.0003304448,0.0002778692,0.0002326796,0.0002009562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01199861,0.0001301155,0.01109675,0.0000227091,0.0001428836,0.0001216009,0.0000239211,0.00006345883,0.9512548,0.000008218486,0.000006976933,0.02512997],"study_design_scores_gemma":[0.003712299,0.02569144,0.002696849,0.00003192613,0.00005045173,0.00148974,0.00004097218,0.002009434,0.9617235,0.0001942094,0.002103931,0.0002552417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9252418,0.004957203,0.06893854,0.000156358,0.0001082357,0.0005726311,0.000003277906,0.000007001127,0.00001489754],"genre_scores_gemma":[0.8777704,0.0004084936,0.1212339,0.000139439,0.000346282,0.00002662112,0.000002537969,0.00003653628,0.00003581593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05229535,"threshold_uncertainty_score":0.6162584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07323151288724694,"score_gpt":0.3792732107365001,"score_spread":0.3060416978492531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}