{"id":"W2121038174","doi":"10.1093/jpids/pit017","title":"Implications of Age-Dependent Immune Responses to Enterovirus 71 Infection for Disease Pathogenesis and Vaccine Design","year":2013,"lang":"en","type":"review","venue":"Journal of the Pediatric Infectious Diseases Society","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Centers for Disease Control and Prevention; Chinese Center for Disease Control and Prevention","keywords":"Enterovirus 71; Medicine; Immune system; Immunology; Disease; Vaccination; Immunity; Acquired immune system; Pandemic; Enterovirus; Virology; Virus; Infectious disease (medical specialty); Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006930905,0.0003789121,0.001430868,0.0004507406,0.0003950143,0.0000651488,0.0002408228,0.000252536,0.00003218997],"category_scores_gemma":[0.001061037,0.0002410735,0.00234909,0.0008725609,0.0001119167,0.0001470222,0.0002326297,0.0005318332,0.000007658556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000428957,"about_ca_system_score_gemma":0.001190525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003879835,"about_ca_topic_score_gemma":0.000001366254,"domain_scores_codex":[0.9973796,0.0004918358,0.00118701,0.0002916832,0.0003101534,0.0003397076],"domain_scores_gemma":[0.996259,0.0007659175,0.001255022,0.0005638002,0.0008095266,0.0003467688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0011805,0.003432337,0.3796174,0.02914465,0.004708252,0.00001945117,0.0002146053,0.00007172238,0.000408661,0.00004494107,0.01738851,0.563769],"study_design_scores_gemma":[0.01339137,0.01304406,0.4407427,0.009638006,0.1196337,0.007089574,0.0001607287,0.00007470653,0.00004198535,0.001817367,0.3919162,0.002449506],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02487764,0.9663764,0.004430473,0.0002140168,0.0005708408,0.003211021,0.0002804469,0.0000318254,0.000007295642],"genre_scores_gemma":[0.0114429,0.9867012,0.0002207938,0.00009856984,0.0007078757,0.000479925,0.00001395037,0.00006768385,0.0002671007],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5613195,"threshold_uncertainty_score":0.9830693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05690854735892253,"score_gpt":0.3638069441682685,"score_spread":0.3068983968093459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}