{"id":"W2121042424","doi":"10.1371/journal.pgen.1005627","title":"Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; University of California, San Francisco; National Institutes of Health","keywords":"Ciliopathy; Ciliopathies; Ciliogenesis; Cilium; Biology; Nephronophthisis; Intraflagellar transport; Genetics; Bardet–Biedl syndrome; Cell biology; Cystic kidney disease; Phenotype; Mutant; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000190704,0.0007194843,0.0003139491,0.000520892,0.0003571116,0.0004632249,0.0004621194,0.0005141069,0.0009482657],"category_scores_gemma":[0.0004024618,0.000317613,0.0003438052,0.0001425593,0.0004948886,0.0002787083,0.001089099,0.0005860162,0.0003676951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000822897,"about_ca_system_score_gemma":0.0003862105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001276563,"about_ca_topic_score_gemma":0.002515876,"domain_scores_codex":[0.9995871,0.00005445731,0.00004234968,0.00008162671,0.0001761018,0.00005839899],"domain_scores_gemma":[0.9996095,0.00005633554,0.0001311759,0.00005897408,0.00004199173,0.0001020173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003204136,0.000006422491,0.0003189811,0.000023774,0.000007421521,0.0001192406,0.000007029987,0.00005886849,0.9986003,0.0001745166,0.00002992459,0.0006215549],"study_design_scores_gemma":[0.00003771823,0.000139842,0.02796517,0.00002717154,0.00006082709,0.001665949,0.00005409388,0.003286903,0.9621783,0.0002490367,0.004315015,0.00001994992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844975,0.003026107,0.008753167,0.0002360257,0.00006888537,0.00005261359,0.0002969748,0.0004159205,0.002652769],"genre_scores_gemma":[0.9942543,0.0005707279,0.004039705,0.00004318272,0.000008044788,0.00002862665,0.0001709797,0.00003063878,0.0008537774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001276563,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05567789245537652,"score_gpt":0.274345809944902,"score_spread":0.2186679174895255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}