{"id":"W2121070277","doi":"10.1038/sj.emboj.7601255","title":"DNA‐PK autophosphorylation facilitates Artemis endonuclease activity","year":2006,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":322,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Autophosphorylation; Endonuclease; DNA; Genetics; Computational biology; Cell biology; Biochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002265728,0.0003571999,0.0002812028,0.0002319214,0.0002364738,0.0006043801,0.000328819,0.0003305587,0.003893106],"category_scores_gemma":[0.0004228639,0.0002971315,0.0002503862,0.0000939486,0.0003202375,0.0007401049,0.0006419704,0.001006524,0.001450607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004863954,"about_ca_system_score_gemma":0.0002855939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003022446,"about_ca_topic_score_gemma":0.0005513053,"domain_scores_codex":[0.999854,0.00001887358,0.00001652789,0.00004069013,0.00003543169,0.00003451167],"domain_scores_gemma":[0.9996378,0.0001179606,0.00005834022,0.00008090118,0.00002545941,0.00007934088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002140438,0.00003027787,0.0001833361,0.00003373645,0.00000350784,0.00008372169,0.00001059197,0.00005383933,0.9978086,0.0004035478,0.00004552517,0.001129336],"study_design_scores_gemma":[0.00001167559,0.00004181283,0.001181653,0.000002221655,0.000003032018,0.0001727938,0.00000683822,0.0003953665,0.9974165,0.0001091385,0.0006556376,0.000003274824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868542,0.001995612,0.007130465,0.0002342117,0.0001450079,0.00002369642,0.00019324,0.0003314122,0.00309211],"genre_scores_gemma":[0.995438,0.0003285818,0.001570752,0.00002899086,0.00001810436,0.000008979751,0.0002240041,0.00004451661,0.002337977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003893106,"threshold_uncertainty_score":0.01302373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007105743422622469,"score_gpt":0.2176174119120426,"score_spread":0.2105116684894201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}