{"id":"W2121102306","doi":"10.1186/ar3632","title":"Cartilage-specific deletion of prar-gamma in mice results in early endochondral ossification defects and accelerated aging-dependent development of osteoarthritis","year":2012,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Shriners Hospitals for Children - Canada; Université de Montréal","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Deutsche Forschungsgemeinschaft","keywords":"Endochondral ossification; Cartilage; Osteoarthritis; Rheumatology; Medicine; Internal medicine; Ossification; Pathology; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005850515,0.001901091,0.0005810352,0.003035041,0.0003655332,0.0007062588,0.001256918,0.001730286,0.01487357],"category_scores_gemma":[0.0003775883,0.0008948556,0.001117325,0.0006601464,0.00119963,0.0006905237,0.0008135483,0.002450494,0.004181706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000638219,"about_ca_system_score_gemma":0.0004373586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005650581,"about_ca_topic_score_gemma":0.001126748,"domain_scores_codex":[0.9991516,0.0001017009,0.00009219839,0.0002645225,0.0002428907,0.0001471123],"domain_scores_gemma":[0.9986944,0.000221117,0.0005922834,0.0001594702,0.00004455617,0.0002882715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002424103,0.0000700222,0.0002121901,0.00006966192,0.00001793523,0.0003936087,0.00003998205,0.000137706,0.9961773,0.0005723156,0.0001483851,0.001918516],"study_design_scores_gemma":[0.0002497673,0.0009611924,0.0104444,0.0001436733,0.0001101432,0.004189371,0.0001600546,0.002074108,0.9703822,0.000633504,0.01060898,0.00004258581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9288282,0.004974134,0.0392801,0.001031928,0.0003324146,0.0003866128,0.01083085,0.00306419,0.0112716],"genre_scores_gemma":[0.9131507,0.004319158,0.02385096,0.0004155235,0.000119679,0.0006770044,0.006785907,0.001200055,0.04948102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01487357,"threshold_uncertainty_score":0.049757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04706617957932111,"score_gpt":0.3213546279715748,"score_spread":0.2742884483922536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}