{"id":"W2121120744","doi":"10.1200/jco.2003.02.098","title":"Comparison of Gemcitabine Versus the Matrix Metalloproteinase Inhibitor BAY 12-9566 in Patients With Advanced or Metastatic Adenocarcinoma of the Pancreas: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":397,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Gemcitabine; Medicine; Interim analysis; Pancreatic cancer; Clinical endpoint; Internal medicine; Oncology; Clinical trial; Cancer; Bay; Adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001714109,0.001196408,0.002228535,0.0004123058,0.000472299,0.0009818223,0.0008140827,0.001045557,0.003326854],"category_scores_gemma":[0.001269222,0.0004239383,0.001580588,0.0006710953,0.0008346945,0.0004107389,0.000261214,0.002209473,0.0004210967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002680129,"about_ca_system_score_gemma":0.004985616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02047382,"about_ca_topic_score_gemma":0.06568077,"domain_scores_codex":[0.9994481,0.0002968114,0.00003625468,0.00006107405,0.00007382086,0.00008385687],"domain_scores_gemma":[0.9993042,0.0001238909,0.0001859601,0.000032228,0.00005548941,0.0002981988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9519539,0.005541773,0.001298376,0.0007325521,0.001134814,0.00005027459,0.00005639069,0.0005932719,0.00268788,0.0001213227,0.0009593258,0.03487006],"study_design_scores_gemma":[0.895138,0.09622432,0.005295814,0.00006019559,0.0008510672,0.00005473705,0.00003037738,0.0005577005,0.0005132739,0.00008125325,0.001177564,0.00001569775],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767721,0.01513527,0.0003484886,0.001041752,0.000360615,0.003316929,0.0006860825,0.00005594427,0.002282768],"genre_scores_gemma":[0.9822692,0.0103409,0.001050992,0.001039995,0.0003258586,0.001643873,0.0008279916,0.00001339656,0.002487764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02047382,"threshold_uncertainty_score":0.04070926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2971718577144146,"score_gpt":0.5606920091573374,"score_spread":0.2635201514429228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}