{"id":"W2121187319","doi":"10.1161/strokeaha.113.002707","title":"Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease","year":2013,"lang":"en","type":"review","venue":"Stroke","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":336,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Heart Research Centre; University of Ottawa","funders":"Institute of Genetics; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research; National Institute on Aging; U.S. Public Health Service; National Institutes of Health; Technische Universität München; School of Medicine, Stanford University; Universität zu Lübeck; Institute for Translational Medicine and Therapeutics; Canadian Institutes of Health Research; University of Ottawa; University of Texas Health Science Center at Houston; Deutsches Zentrum für Herz-Kreislaufforschung; Imperial College London; Broad Institute; National Institute of Neurological Disorders and Stroke; British Heart Foundation; University of Pennsylvania; National Human Genome Research Institute; Tays; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; University of Leeds; School of Medicine, Boston University","keywords":"Genome-wide association study; Coronary artery disease; Medicine; Heritability; Genetic association; Genetics; Internal medicine; Disease; Stroke (engine); Clinical significance; Cardiology; Bioinformatics; Single-nucleotide polymorphism; Biology; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002458401,0.000905419,0.001649054,0.001844338,0.0005061969,0.001460353,0.0009460102,0.001110044,0.003170373],"category_scores_gemma":[0.006173762,0.000507821,0.002788832,0.003433616,0.001127618,0.0004537755,0.001714653,0.0008303892,0.0002258033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005409345,"about_ca_system_score_gemma":0.0006514594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004404332,"about_ca_topic_score_gemma":0.004387868,"domain_scores_codex":[0.9959272,0.001451452,0.000415861,0.001361235,0.0004398567,0.0004043877],"domain_scores_gemma":[0.9953028,0.001658798,0.001504938,0.0008778536,0.0003147811,0.000340857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"systematic_review","study_design_scores_codex":[0.001489085,0.00009600663,0.9378213,0.0007244785,0.03480144,0.001172005,0.000187259,0.001922589,0.003348688,0.001263974,0.0005632857,0.01661],"study_design_scores_gemma":[0.0002771214,0.0003610865,0.9721915,0.000251949,0.0156846,0.002181757,0.0001559486,0.002014011,0.0007737178,0.004875239,0.001196669,0.00003628451],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9630657,0.0262983,0.004783554,0.0008127467,0.0001288493,0.00004948231,0.002189535,0.0000970656,0.002574753],"genre_scores_gemma":[0.9955303,0.002429483,0.0008176136,0.00009450277,0.0001013976,0.00002253298,0.000802932,0.000009716857,0.0001915596],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004404332,"threshold_uncertainty_score":0.01300144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02674046924647743,"score_gpt":0.2994880646779639,"score_spread":0.2727475954314864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}