{"id":"W2121187319","doi":"10.1161/strokeaha.113.002707","title":"Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease","year":2013,"lang":"en","type":"review","venue":"Stroke","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":336,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Heart Research Centre; University of Ottawa","funders":"Institute of Genetics; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research; National Institute on Aging; U.S. Public Health Service; National Institutes of Health; Technische Universität München; School of Medicine, Stanford University; Universität zu Lübeck; Institute for Translational Medicine and Therapeutics; Canadian Institutes of Health Research; University of Ottawa; University of Texas Health Science Center at Houston; Deutsches Zentrum für Herz-Kreislaufforschung; Imperial College London; Broad Institute; National Institute of Neurological Disorders and Stroke; British Heart Foundation; University of Pennsylvania; National Human Genome Research Institute; Tays; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; University of Leeds; School of Medicine, Boston University","keywords":"Genome-wide association study; Coronary artery disease; Medicine; Heritability; Genetic association; Genetics; Internal medicine; Disease; Stroke (engine); Clinical significance; Cardiology; Bioinformatics; Single-nucleotide polymorphism; Biology; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002053325,0.0004738673,0.0009550101,0.00008121363,0.00009593225,0.00003882221,0.0003347275,0.0004692072,0.000173904],"category_scores_gemma":[0.0002770228,0.0004229996,0.0003741881,0.00006566988,0.0000998786,0.000002973974,0.0004073995,0.0002206007,0.0002302484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004870107,"about_ca_system_score_gemma":0.0002535171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001432337,"about_ca_topic_score_gemma":0.00002682727,"domain_scores_codex":[0.9976071,0.0002375228,0.0005953717,0.0009458106,0.0001284936,0.0004857284],"domain_scores_gemma":[0.9983217,0.00005621733,0.0002324657,0.0008429818,0.00008405602,0.000462634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003056744,0.0001285316,0.01919356,0.002494719,0.0005646186,0.0000160025,0.0000163298,0.000005111714,0.001044095,0.00000534837,0.1042241,0.872277],"study_design_scores_gemma":[0.0002035087,0.0001689004,0.01345993,0.0002363774,0.0002854662,0.00003339094,0.00001324168,0.000005667687,0.00000467533,0.00001103532,0.9851277,0.000450031],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03419178,0.961615,0.0001759478,0.00006656403,0.000222783,0.001108026,0.001839202,0.00001915665,0.0007614967],"genre_scores_gemma":[0.004260637,0.9811459,0.002633373,0.0002195775,0.0004579652,0.0004116798,0.00143193,0.00006794824,0.00937102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8809037,"threshold_uncertainty_score":0.9998222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02674046924647743,"score_gpt":0.2994880646779639,"score_spread":0.2727475954314864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}