{"id":"W2121200335","doi":"10.1109/memb.2006.1657790","title":"A viral envelope as a vehicle for tracer, drug, and gene delivery","year":2006,"lang":"en","type":"article","venue":"IEEE Engineering in Medicine and Biology Magazine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biodistribution; Positron emission tomography; Drug delivery; Biomedical engineering; Gene delivery; Medicine; Drug; Radioactive tracer; Viral vector; Medical physics; Nuclear medicine; Genetic enhancement; Pharmacology; Nanotechnology; Materials science; Chemistry; Recombinant DNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003074927,0.000155755,0.0002043924,0.0001124376,0.00003188887,0.000005253522,0.00008312451,0.0001278987,0.000008074703],"category_scores_gemma":[0.00004704108,0.0001312234,0.00002415302,0.00007763319,0.0001284327,0.000003383439,0.00003137054,0.000105607,0.000002549311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009627894,"about_ca_system_score_gemma":0.00002641651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006689427,"about_ca_topic_score_gemma":0.0001262379,"domain_scores_codex":[0.9991447,0.00002768627,0.0001881653,0.0003071772,0.00004501499,0.000287244],"domain_scores_gemma":[0.9996989,0.00004760715,0.00002458801,0.0001313218,0.00003559937,0.00006199272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004757062,0.00002242037,0.002804487,0.00003134256,0.00002206645,0.000005815846,0.00002632303,0.0001967578,0.9919887,0.00003171632,0.001710894,0.002683798],"study_design_scores_gemma":[0.01464214,0.01280313,0.03409157,0.0001230056,0.00006198107,0.0001661538,0.00005471371,0.007909522,0.835455,0.0006160101,0.09312674,0.000950044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917976,0.006832072,0.0003760997,0.0005777231,0.00009515982,0.000220955,0.000009183545,0.00001471732,0.00007651263],"genre_scores_gemma":[0.9967486,0.001300518,0.0005117382,0.0002710725,0.0005562766,0.00005271159,0.00007949762,0.00002184092,0.000457771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1565337,"threshold_uncertainty_score":0.5351136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529596600480328,"score_gpt":0.2827122640203452,"score_spread":0.2674162980155419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}