{"id":"W2121210416","doi":"10.1371/journal.pone.0008072","title":"Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Centre for Disease Control","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health; University of Hong Kong; University Grants Committee","keywords":"Influenza A virus subtype H5N1; Biology; Influenza A virus; Interferon; Virus; Virology; Immunology; Tumor necrosis factor alpha; Pathogenesis; Cytokine; Viral shedding; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003119463,0.0002087802,0.000470644,0.0001746722,0.0001669739,0.0003981339,0.0001793868,0.0002672873,0.0005878634],"category_scores_gemma":[0.0001417226,0.0001158544,0.0003565345,0.0002329928,0.0001606861,0.0002072288,0.0001550814,0.0002567246,0.0001942858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003583335,"about_ca_system_score_gemma":0.0002091495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007248092,"about_ca_topic_score_gemma":0.001345903,"domain_scores_codex":[0.9997308,0.0000618223,0.00001888666,0.00008156061,0.00006379253,0.00004322701],"domain_scores_gemma":[0.9998966,0.00004158369,0.00001846626,0.00001036614,0.00002224531,0.00001057857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000283877,0.000041592,0.001786597,0.0001413123,0.00003251532,0.00002089396,0.00002650797,0.0004244566,0.9956228,0.00004859492,0.00004610982,0.001524715],"study_design_scores_gemma":[0.00002780057,0.001787784,0.1030237,0.00001997323,0.0002274284,0.0002100008,0.0002698508,0.01184724,0.8793647,0.0003911229,0.00279975,0.00003061941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914178,0.001929234,0.003640808,0.00008079323,0.00003116345,0.00004898642,0.001960404,0.0000635966,0.0008271586],"genre_scores_gemma":[0.9896237,0.001399954,0.004979962,0.00007893384,0.00002047074,0.000126394,0.00313583,0.000007776016,0.0006269109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007248092,"threshold_uncertainty_score":0.002599895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2129884899327808,"score_gpt":0.3990446769843649,"score_spread":0.186056187051584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}