{"id":"W2121275583","doi":"10.1002/eji.200535687","title":"Revisiting the specificity of the MHC class II transactivator CIITA <i>in vivo</i>","year":2006,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Ligue Genevoise Contre le Cancer; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"CIITA; Biology; MHC class II; Major histocompatibility complex; MHC class I; Antigen presentation; Gene; Antigen processing; Cell biology; Immune system; Genetics; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001111359,0.0001444954,0.0002981538,0.000115812,0.0002483937,0.00001022411,0.0005401624,0.00007260454,0.0008698649],"category_scores_gemma":[0.0001081316,0.00008331134,0.0002571973,0.0001991906,0.0003179514,0.0001164479,0.0000787075,0.0009271501,0.00005965066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005362253,"about_ca_system_score_gemma":0.00004271143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003793634,"about_ca_topic_score_gemma":0.000004315913,"domain_scores_codex":[0.9972311,0.001467817,0.0008938224,0.0001217474,0.00005009734,0.0002353674],"domain_scores_gemma":[0.9985428,0.0001863543,0.0008092939,0.0003086342,0.0001467464,0.000006171601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004224109,0.00009480049,0.0006198782,0.000005140741,0.0001118387,0.00001092091,0.0003234886,0.00005477696,0.9870132,0.0005567483,0.007208444,0.003578405],"study_design_scores_gemma":[0.001675809,0.0003281329,0.0460804,0.0001392635,0.00004334556,0.0008107048,0.0008161355,0.000002005416,0.3926078,0.00003777079,0.5573446,0.000114121],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9592214,0.004759541,0.0003719759,0.003053637,0.00498818,0.0001168177,0.000003173059,0.00001189426,0.02747342],"genre_scores_gemma":[0.9937414,0.0001503902,0.0000141978,0.0002040631,0.0001714122,5.089483e-7,0.000001569767,0.00001840802,0.005698056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5944054,"threshold_uncertainty_score":0.9524412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008588576612724537,"score_gpt":0.1930260721183884,"score_spread":0.1844374955056639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}