{"id":"W2121275583","doi":"10.1002/eji.200535687","title":"Revisiting the specificity of the MHC class II transactivator CIITA <i>in vivo</i>","year":2006,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Ligue Genevoise Contre le Cancer; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"CIITA; Biology; MHC class II; Major histocompatibility complex; MHC class I; Antigen presentation; Gene; Antigen processing; Cell biology; Immune system; Genetics; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005522565,0.0004892936,0.0002563252,0.0002266957,0.0001997362,0.0007541322,0.0005985507,0.000414439,0.001287645],"category_scores_gemma":[0.0002912007,0.000190354,0.0002330163,0.0001400449,0.0006356412,0.0005923976,0.0004428367,0.001354413,0.0007924757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005707154,"about_ca_system_score_gemma":0.0002410813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004864321,"about_ca_topic_score_gemma":0.0005858341,"domain_scores_codex":[0.9996835,0.00005321921,0.00002169646,0.00009879217,0.0000696717,0.00007309502],"domain_scores_gemma":[0.9997813,0.00006236193,0.00004557734,0.00004017996,0.00003850003,0.00003213921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005449469,0.000008488296,0.0002794696,0.00003973033,0.000001484538,0.00003283169,0.00001806795,0.00004516257,0.9973252,0.0003732177,0.00003426259,0.001787628],"study_design_scores_gemma":[0.000007267943,0.00008570711,0.003356656,0.00001802934,0.00001483693,0.0004422301,0.00005139934,0.001025547,0.9869781,0.0002530618,0.007760177,0.000006952516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9368402,0.02508579,0.02789109,0.000989243,0.0001866082,0.0000485663,0.0002990983,0.0001622244,0.008497126],"genre_scores_gemma":[0.9839131,0.005923939,0.005768764,0.0002996734,0.0001222944,0.00004023432,0.0004013627,0.00007097654,0.003459635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001287645,"threshold_uncertainty_score":0.004307568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008588576612724537,"score_gpt":0.1930260721183884,"score_spread":0.1844374955056639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}