{"id":"W2121318650","doi":"10.1128/mcb.00353-09","title":"Cooperative Action of Multiple<i>cis</i>-Acting Elements Is Required for N-<i>myc</i>Expression in Branchial Arches: Specific Contribution of GATA3","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Cancer Research Society","keywords":"Enhancer; Biology; Branchial arch; Somite; Limb bud; Intron; Transcription factor; Enhancer RNAs; Ectopic expression; Cell biology; Limb development; Gene; Transgene; Gene expression; Regulation of gene expression; Genetics; Embryonic stem cell; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001343968,0.0003658656,0.0002622598,0.0001480461,0.0001582406,0.000326297,0.0002278418,0.0002157175,0.0008431129],"category_scores_gemma":[0.000204865,0.0003327305,0.0002223937,0.00007592583,0.0003311286,0.0001840034,0.0002865209,0.0004757786,0.0005713694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003127422,"about_ca_system_score_gemma":0.000308566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007355827,"about_ca_topic_score_gemma":0.001575403,"domain_scores_codex":[0.9998043,0.00002357899,0.00001394562,0.00005468463,0.00005814257,0.00004535738],"domain_scores_gemma":[0.9997602,0.00004927601,0.00005240099,0.00003091588,0.00002202616,0.00008514155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002083292,0.000003025354,0.000214112,0.000004379308,6.966216e-7,0.00002264718,0.000005007297,0.00001657606,0.9995056,0.00002960348,0.000004009538,0.0001734261],"study_design_scores_gemma":[0.00001154658,0.00006609754,0.01474152,0.000004102174,0.0000088072,0.0004409776,0.00002120917,0.001059737,0.9829394,0.00008022515,0.0006221554,0.000004152018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958956,0.0003331344,0.002598213,0.00002645581,0.000005332238,0.000007980238,0.00009169283,0.0000749162,0.00096661],"genre_scores_gemma":[0.9967996,0.0001428019,0.001731094,0.00001674707,0.000003764088,0.00001181813,0.000291969,0.00004748464,0.0009546294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008431129,"threshold_uncertainty_score":0.002820492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0206600002092456,"score_gpt":0.3072820619823927,"score_spread":0.2866220617731471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}