{"id":"W2121335553","doi":"10.1523/jneurosci.20-13-04855.2000","title":"Excitatory Role of the Hyperpolarization-Activated Inward Current in Phasic and Tonic Firing of Rat Supraoptic Neurons","year":2000,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"Medical Research Council","keywords":"Hyperpolarization (physics); Chemistry; Depolarization; Excitatory postsynaptic potential; Membrane potential; Neuroscience; Electrophysiology; Biophysics; Tonic (physiology); Bursting; Patch clamp; Supraoptic nucleus; Current clamp; Voltage clamp; Hypothalamus; Biology; Inhibitory postsynaptic potential; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000733804,0.000212971,0.0002621543,0.0001282303,0.00007293894,0.0001795739,0.0001777331,0.0001394727,0.0005247612],"category_scores_gemma":[0.0001566095,0.0001154824,0.0001678103,0.00008655922,0.0001812964,0.0002200883,0.0001770837,0.0003096124,0.0001264618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002259539,"about_ca_system_score_gemma":0.0001377003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006219246,"about_ca_topic_score_gemma":0.001104122,"domain_scores_codex":[0.9999434,0.000005539635,0.000008060075,0.00001164774,0.00001254432,0.00001884293],"domain_scores_gemma":[0.9998966,0.00001327171,0.00003810468,0.00001071185,0.0000125465,0.00002864754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001270799,0.000005130802,0.0004826659,0.00002185303,0.000002843246,0.0000605965,0.00001175579,0.00001387336,0.9982333,0.00001884288,0.000004841725,0.001017059],"study_design_scores_gemma":[0.00002665681,0.0005651887,0.1014201,0.00001644125,0.00004361804,0.0004408998,0.0001167382,0.0006676265,0.8959407,0.00007753275,0.0006776326,0.000006911585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979957,0.001008629,0.0004381899,0.00001779926,0.000004734695,0.000005962512,0.00007735335,0.00002063416,0.0004310443],"genre_scores_gemma":[0.9980932,0.0007971418,0.0005193109,0.00001886472,0.000006801326,0.00000914932,0.0001076833,0.000005863231,0.000442058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006219246,"threshold_uncertainty_score":0.001755476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04369329320436454,"score_gpt":0.3315447031996479,"score_spread":0.2878514099952834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}