{"id":"W2121338172","doi":"10.1128/aac.00334-11","title":"Recombinant Phenotyping of Cytomegalovirus UL54 Mutations That Emerged during Cell Passages in the Presence of either Ganciclovir or Foscarnet","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec; Centre Hospitalier Universitaire de Sherbrooke","funders":"Canadian Institutes of Health Research; Purdue University","keywords":"Foscarnet; Ganciclovir; Biology; Polymerase; Virology; Human cytomegalovirus; Mutation; DNA polymerase; Valganciclovir; Mutant; Point mutation; Drug resistance; Molecular biology; Virus; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001634436,0.0003336593,0.0002526394,0.0003321036,0.0001367883,0.000237674,0.0002353886,0.0003469857,0.0005557169],"category_scores_gemma":[0.0002727877,0.0001392582,0.0002740781,0.0003094595,0.0001487414,0.0001218267,0.0001876743,0.0003707837,0.0002167178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003654544,"about_ca_system_score_gemma":0.0001256718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001499682,"about_ca_topic_score_gemma":0.001356327,"domain_scores_codex":[0.9997863,0.0000411706,0.00002713302,0.00004375455,0.00005705112,0.00004446724],"domain_scores_gemma":[0.9998511,0.00004650945,0.00003414979,0.00002433749,0.00002104851,0.00002269653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003680145,0.00002396809,0.0005340155,0.000007137852,0.000003300284,0.00004150638,0.00001488046,0.0001036397,0.9986354,0.00002944559,0.00000967096,0.000560257],"study_design_scores_gemma":[0.000007136864,0.0003545106,0.008751307,0.000003495368,0.00001618446,0.0003173231,0.00003592573,0.002280829,0.9875976,0.0000262924,0.0006036564,0.000005627958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973093,0.0001484257,0.001621858,0.00001616471,0.000006965989,0.000031401,0.0004260129,0.00002556543,0.0004141555],"genre_scores_gemma":[0.9939711,0.0002119814,0.003759346,0.00001615627,0.000003200805,0.00004595205,0.0008815938,0.00002377096,0.001086929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001499682,"threshold_uncertainty_score":0.002981842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05638247178849676,"score_gpt":0.2961770368674385,"score_spread":0.2397945650789417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}