{"id":"W2121372003","doi":"10.1128/jvi.74.18.8541-8549.2000","title":"Identification of Dominant Optimal HLA-B60- and HLA-B61-Restricted Cytotoxic T-Lymphocyte (CTL) Epitopes: Rapid Characterization of CTL Responses by Enzyme-Linked Immunospot Assay","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CTL*; ELISPOT; Epitope; Biology; Human leukocyte antigen; Cytotoxic T cell; Immunology; Virology; Immune system; Antigen; T cell; CD8; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009555066,0.000209915,0.0006764925,0.0003746611,0.0001250015,0.00001516642,0.0003055606,0.0003558795,0.000806951],"category_scores_gemma":[0.0002712397,0.0001691233,0.000150894,0.0002139277,0.0004833468,0.0002075002,0.00004977705,0.0003229825,0.00008095865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008540398,"about_ca_system_score_gemma":0.0002326456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003752293,"about_ca_topic_score_gemma":0.000002179728,"domain_scores_codex":[0.9969158,0.001144036,0.001219597,0.0002359491,0.0001225626,0.0003620963],"domain_scores_gemma":[0.9979317,0.000443839,0.001027664,0.0002829039,0.0002522925,0.00006163968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008196223,0.0005597009,0.0007314064,0.00002302767,0.0004754013,0.00003674061,0.0003748427,0.00001015554,0.9649051,0.00001746663,0.0003273017,0.02434263],"study_design_scores_gemma":[0.005722419,0.002769916,0.1057519,0.00004708947,0.0001484786,0.0005967803,0.00007296573,0.00002864531,0.8769234,0.00002000683,0.007782154,0.0001362051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921272,0.006312764,0.0003803873,0.0003691742,0.0002122441,0.000283063,0.0002783475,0.000008385744,0.00002840203],"genre_scores_gemma":[0.989207,0.009315318,0.00007378477,0.00003904039,0.00003531419,0.00001266838,0.0001888502,0.00001765423,0.001110421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1050205,"threshold_uncertainty_score":0.8835548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008302872094232206,"score_gpt":0.2488620642101071,"score_spread":0.240559192115875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}