{"id":"W2121372003","doi":"10.1128/jvi.74.18.8541-8549.2000","title":"Identification of Dominant Optimal HLA-B60- and HLA-B61-Restricted Cytotoxic T-Lymphocyte (CTL) Epitopes: Rapid Characterization of CTL Responses by Enzyme-Linked Immunospot Assay","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CTL*; ELISPOT; Epitope; Biology; Human leukocyte antigen; Cytotoxic T cell; Immunology; Virology; Immune system; Antigen; T cell; CD8; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002494022,0.0002520259,0.0002814356,0.0003127982,0.0001637616,0.0003641064,0.0001179418,0.0003810138,0.001015819],"category_scores_gemma":[0.0003363268,0.00009605321,0.0001441939,0.0001791504,0.000152703,0.0001694558,0.0001721935,0.0003823336,0.0004857377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008471979,"about_ca_system_score_gemma":0.00007243177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001596483,"about_ca_topic_score_gemma":0.0001411102,"domain_scores_codex":[0.9998198,0.00003364791,0.00002383774,0.00003977539,0.00004703109,0.00003592399],"domain_scores_gemma":[0.9998268,0.00006113905,0.00002274096,0.0000190942,0.00003207757,0.00003815275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001574591,0.00005390347,0.002616459,0.0000277758,0.000004004854,0.00005849101,0.00004581193,0.00005584446,0.993499,0.00004771298,0.00001785875,0.003415582],"study_design_scores_gemma":[0.00007916552,0.001281308,0.04601282,0.00001652306,0.00003217314,0.00230492,0.0001353174,0.002405119,0.9455881,0.0003993436,0.001730354,0.00001498625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918108,0.0004188853,0.006768591,0.00001598177,0.000006968825,0.00005009312,0.0001709908,0.00003170114,0.0007259879],"genre_scores_gemma":[0.9916193,0.0002515302,0.007138609,0.00003492196,0.000007658427,0.00004524904,0.0003229003,0.00001030155,0.0005694175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015819,"threshold_uncertainty_score":0.00339824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008302872094232206,"score_gpt":0.2488620642101071,"score_spread":0.240559192115875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}