{"id":"W2121396361","doi":"10.1093/neuonc/nos273","title":"Standards of care for treatment of recurrent glioblastoma—are we there yet?","year":2012,"lang":"en","type":"review","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":771,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Temozolomide; Bevacizumab; Medicine; Oncology; Glioblastoma; Adjuvant; Concomitant; Clinical trial; Internal medicine; Standard of care; Radiation therapy; Chemotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004611868,0.0009644277,0.002402359,0.002706186,0.0004811991,0.002188386,0.002093018,0.00230116,0.002731793],"category_scores_gemma":[0.01029048,0.0004058683,0.0009961553,0.004139612,0.001287911,0.003912037,0.001026015,0.003357063,0.001425667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00276748,"about_ca_system_score_gemma":0.008721367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004516213,"about_ca_topic_score_gemma":0.007531527,"domain_scores_codex":[0.997779,0.0005770453,0.000554358,0.000131881,0.0008763166,0.00008150789],"domain_scores_gemma":[0.9955205,0.001630001,0.001106327,0.0001438776,0.001409201,0.0001901453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005891653,0.00004972491,0.0002734396,0.03621944,0.0001643711,0.00007741308,0.0001397018,0.000187415,0.0002554066,0.007662563,0.08195978,0.8729517],"study_design_scores_gemma":[0.00005163704,0.00006211633,0.001299818,0.06816211,0.0002985738,0.0004624139,0.0002805516,0.00007992738,0.000122606,0.006066564,0.9230794,0.00003419471],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004597961,0.9935871,0.000115883,0.004869977,0.0006601824,0.0000116801,0.00002064526,0.000007449827,0.0006809768],"genre_scores_gemma":[0.0006626719,0.9962758,0.0006143817,0.001868259,0.0002950671,0.00002258666,0.00003895634,0.000002745409,0.0002196205],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004611868,"threshold_uncertainty_score":0.02439016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07411255517976502,"score_gpt":0.4022211541986221,"score_spread":0.3281085990188571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}