{"id":"W2121435941","doi":"10.1158/0008-5472.can-04-3666","title":"Gene Therapy for Prostate Cancer by Controlling Adenovirus <i>E1a</i> and <i>E4</i> Gene Expression with PSES Enhancer","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Enhancer; Genetic enhancement; Prostate cancer; Cancer research; Gene; Gene expression; Prostate; Biology; Cancer; Medicine; Oncology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00085481,0.000293278,0.0002910807,0.0001049365,0.0004241071,0.0001226729,0.0004068691,0.0001851055,0.0001165365],"category_scores_gemma":[0.00003343904,0.0002287986,0.00006923364,0.0002383921,0.0003779971,0.0000217979,0.000133386,0.0003352858,0.0000059399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001190691,"about_ca_system_score_gemma":0.0006015814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002439365,"about_ca_topic_score_gemma":0.0006314879,"domain_scores_codex":[0.9970058,0.0002129931,0.000254937,0.0008798566,0.0006376223,0.001008765],"domain_scores_gemma":[0.9984658,0.00007671276,0.00008079644,0.0005138147,0.0005884524,0.0002743618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01604805,0.00009114717,0.0006648778,0.00003578571,0.0001207872,0.000001883904,0.0001286379,0.0002997676,0.9096319,8.425963e-7,0.0106764,0.06229988],"study_design_scores_gemma":[0.004271107,0.00231328,0.00002052514,0.00005022277,0.000007790505,0.0000027463,0.00004912044,0.00005368731,0.8917524,0.00001451824,0.1011827,0.0002818675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.904929,0.09102508,0.0003738457,0.001500615,0.00005224979,0.001613943,0.0004099848,0.00002130888,0.0000739711],"genre_scores_gemma":[0.9169856,0.07357945,0.0006642134,0.0008816761,0.001055195,0.003780514,0.0001137319,0.0001246807,0.002814906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09050632,"threshold_uncertainty_score":0.9330138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03040548070209521,"score_gpt":0.3702478676122567,"score_spread":0.3398423869101615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}