{"id":"W2121443197","doi":"10.1186/2045-3701-1-15","title":"Subretinal gene delivery using helper-dependent adenoviral vectors","year":2011,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Canada Research Chairs; Toronto Rehabilitation Institute; University of British Columbia; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Gene delivery; Viral vector; Gene transfer; Virology; Genetic enhancement; Biology; Gene; Computational biology; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001549122,0.0001435212,0.0000834802,0.000049705,0.0001452624,0.00003000619,0.0003446465,0.00008468098,0.0000743582],"category_scores_gemma":[0.00001810969,0.0001333365,0.00005836001,0.0001427978,0.0001951815,0.000009811588,0.000167317,0.00005700197,0.00004014167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001682712,"about_ca_system_score_gemma":0.0001346197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008253948,"about_ca_topic_score_gemma":0.00001254654,"domain_scores_codex":[0.998895,0.00002698796,0.0001492654,0.0004129385,0.0001875508,0.0003281814],"domain_scores_gemma":[0.9995636,0.000002577762,0.00006315044,0.0002134666,0.00005295123,0.0001042135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003671212,0.00004483188,0.02746841,0.000005871981,0.000002704788,0.000007701854,0.0001118307,0.000004257153,0.9719069,0.000009462635,0.0001062917,0.0002950443],"study_design_scores_gemma":[0.0002061916,0.00017413,0.02801686,0.000005653771,0.000008668005,0.0000188463,0.000152095,0.000057943,0.9698201,0.0000236611,0.001263877,0.0002519975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928069,0.000539328,0.001031672,0.00001062202,0.0002884794,0.00008716819,0.000003369564,0.00001268265,0.00521979],"genre_scores_gemma":[0.9950334,0.0001351502,0.003821034,0.0001730322,0.00005575887,0.000003076173,0.00001133763,0.00001161097,0.0007555276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004464262,"threshold_uncertainty_score":0.5437306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02832942162602019,"score_gpt":0.2196375338983226,"score_spread":0.1913081122723023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}