{"id":"W2121452217","doi":"10.1139/o09-057","title":"Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancerThis paper is one of a selection of papers published in this Special Issue, entitled The 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal's usual peer review process.","year":2009,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Polycomb-group proteins; Biology; Epigenetics; PRC2; Chromatin; Genomic imprinting; Carcinogenesis; microRNA; Hox gene; Genetics; Gene; Cancer research; DNA methylation; Gene expression; EZH2; Repressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004634709,0.0004011644,0.0004739865,0.0006945083,0.0006579819,0.002482317,0.0004619895,0.0007402284,0.01632348],"category_scores_gemma":[0.0006507923,0.0001286995,0.0001523289,0.00156402,0.0009258682,0.0008971855,0.000741578,0.000936745,0.004258827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008656724,"about_ca_system_score_gemma":0.0008447812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001085787,"about_ca_topic_score_gemma":0.00194684,"domain_scores_codex":[0.9996315,0.00005266602,0.00001731664,0.00006993682,0.0001842845,0.00004432505],"domain_scores_gemma":[0.9996504,0.00005610091,0.00006533483,0.00002459657,0.00007700307,0.0001266813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003268575,0.00009625676,0.002846689,0.00352057,0.0001042549,0.0007152891,0.0002936109,0.0002573735,0.0398093,0.041219,0.3131941,0.5976167],"study_design_scores_gemma":[0.00001399997,0.00005996092,0.005148983,0.0001297194,0.00002007784,0.0005948985,0.0001372443,0.0001436606,0.003885805,0.00696469,0.9828881,0.00001281758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01005731,0.8975271,0.001865474,0.01545709,0.01275616,0.00005757708,0.000736211,0.0002443757,0.06129875],"genre_scores_gemma":[0.1631681,0.5908774,0.001969984,0.004337503,0.01657295,0.0001011412,0.002251803,0.0001288782,0.2205922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01632348,"threshold_uncertainty_score":0.05460745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01796934879559866,"score_gpt":0.2688215843244401,"score_spread":0.2508522355288415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}