{"id":"W2121452217","doi":"10.1139/o09-057","title":"Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancerThis paper is one of a selection of papers published in this Special Issue, entitled The 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal's usual peer review process.","year":2009,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Polycomb-group proteins; Biology; Epigenetics; PRC2; Chromatin; Genomic imprinting; Carcinogenesis; microRNA; Hox gene; Genetics; Gene; Cancer research; DNA methylation; Gene expression; EZH2; Repressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007289653,0.0002904485,0.0006568364,0.00005391535,0.0001166437,0.0000497463,0.0002071739,0.0004063489,0.0005776163],"category_scores_gemma":[0.00006680311,0.0001916465,0.00007898125,0.0001272749,0.000319214,0.00001333846,0.0001181997,0.0002876495,1.926435e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002313021,"about_ca_system_score_gemma":0.0002345169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005688372,"about_ca_topic_score_gemma":0.00003088886,"domain_scores_codex":[0.9984464,0.0001774778,0.0006068073,0.0004011055,0.0001823502,0.0001858387],"domain_scores_gemma":[0.9988031,0.00004480962,0.0006835344,0.000174094,0.0002303093,0.00006415214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005438034,0.00009135799,0.00006158209,0.006864129,0.0001918743,0.000001073978,0.0002788666,2.129455e-7,0.7983137,0.000007194642,0.001136922,0.1929986],"study_design_scores_gemma":[0.0006189165,0.0004344576,0.00006084465,0.003232131,0.0003131228,0.00004194669,0.0001906278,0.00001098831,0.6843022,0.00004838533,0.3104135,0.0003329508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05697954,0.9408079,0.00001120949,0.0003443678,0.00009870599,0.0005184594,0.0001264819,0.000002262047,0.0011111],"genre_scores_gemma":[0.07717934,0.9212207,0.00006043029,0.00006026193,0.0004881287,0.00002462671,0.0001317876,0.00001384877,0.0008209385],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3092765,"threshold_uncertainty_score":0.7815117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01796934879559866,"score_gpt":0.2688215843244401,"score_spread":0.2508522355288415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}