{"id":"W2121534767","doi":"10.1128/iai.01877-14","title":"A Conserved Apicomplexan Microneme Protein Contributes to Toxoplasma gondii Invasion and Virulence","year":2014,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Microneme; Biology; Toxoplasma gondii; Virulence; Apicomplexa; Rhoptry; Microbiology; Plasmodium (life cycle); Virology; Virulence factor; Complementation; Neospora caninum; Intracellular parasite; Plasmodium falciparum; Genetics; Parasite hosting; Phenotype; Gene; Immunology; Malaria; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005729321,0.0001738016,0.0002752142,0.0001742625,0.0006714166,0.00005430342,0.00009062151,0.0001579138,0.00009437312],"category_scores_gemma":[0.0008467192,0.0001526607,0.00003298779,0.0001609658,0.0004067505,0.000109442,0.000340953,0.0003827783,0.0001774423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000374493,"about_ca_system_score_gemma":0.00002540273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0017184,"about_ca_topic_score_gemma":0.0008766525,"domain_scores_codex":[0.9986315,0.0005549766,0.000214753,0.0002533339,0.00003002846,0.0003154066],"domain_scores_gemma":[0.999258,0.0002873015,0.00006423326,0.0002285126,0.0001132563,0.0000486677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001784065,0.00008508234,0.02221012,0.00004845201,0.00008568391,4.562989e-7,0.0002890086,3.776013e-7,0.9653113,0.00148583,0.001050827,0.009254385],"study_design_scores_gemma":[0.002309178,0.000767289,0.3554582,0.0001217588,0.00002159292,0.00006398672,0.0001557813,0.00001483861,0.482484,0.0008293669,0.1575065,0.0002676098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962744,0.0006954634,0.0004802342,0.0009487501,0.0001718699,0.0005659458,0.00001829981,0.0001008606,0.0007441657],"genre_scores_gemma":[0.9981719,0.0001606885,0.00008795856,0.0003072954,0.00001082043,0.00008676457,0.00002149021,0.000009629532,0.001143482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4828274,"threshold_uncertainty_score":0.6225322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741554802406426,"score_gpt":0.2517067374970804,"score_spread":0.2342911894730162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}