{"id":"W2121534767","doi":"10.1128/iai.01877-14","title":"A Conserved Apicomplexan Microneme Protein Contributes to Toxoplasma gondii Invasion and Virulence","year":2014,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Microneme; Biology; Toxoplasma gondii; Virulence; Apicomplexa; Rhoptry; Microbiology; Plasmodium (life cycle); Virology; Virulence factor; Complementation; Neospora caninum; Intracellular parasite; Plasmodium falciparum; Genetics; Parasite hosting; Phenotype; Gene; Immunology; Malaria; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009469639,0.0003882654,0.0002137412,0.0002040978,0.0001620311,0.0002686664,0.0001786637,0.0003198,0.001177264],"category_scores_gemma":[0.000126848,0.0001226869,0.0002485929,0.0001520713,0.0002654683,0.0001484698,0.000291126,0.0005516438,0.000485815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002194636,"about_ca_system_score_gemma":0.0002499543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000755257,"about_ca_topic_score_gemma":0.0006619381,"domain_scores_codex":[0.9998876,0.0000143404,0.0000127008,0.00002006589,0.00004700361,0.00001824431],"domain_scores_gemma":[0.9998491,0.00001577636,0.00005361154,0.00001590872,0.00001778403,0.00004777335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000537862,0.00001031841,0.0005249681,0.0000320687,0.000002822095,0.0001518817,0.00001192726,0.0000513186,0.9984023,0.00006409725,0.00002693685,0.0006675514],"study_design_scores_gemma":[0.00004294635,0.0003788237,0.06917307,0.00002848188,0.00006573522,0.003941591,0.0001598417,0.003896588,0.9140596,0.0002587422,0.007975077,0.00001965562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996644,0.0006126852,0.001299285,0.0001081746,0.00001154897,0.00001363342,0.000220578,0.00006673478,0.001023373],"genre_scores_gemma":[0.9962218,0.000393126,0.001578309,0.00004465681,0.000005726111,0.00001262721,0.000403333,0.00002726569,0.001313198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001177264,"threshold_uncertainty_score":0.003938317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741554802406426,"score_gpt":0.2517067374970804,"score_spread":0.2342911894730162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}