{"id":"W2121545064","doi":"10.1016/j.bbrc.2006.10.043","title":"Enhanced intrinsic migration of aggressive breast cancer cells by inhibition of Rac1 GTPase","year":2006,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Western University","keywords":"RAC1; RHOA; Cell migration; GTPase; Cell biology; Cell; Rac GTP-Binding Proteins; Cancer cell; CDC42; Biology; Cancer research; Metastasis; Chemistry; Cancer; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001223689,0.0003538487,0.0003040313,0.0002298512,0.0002060917,0.0003655672,0.0002036597,0.0002227606,0.001274183],"category_scores_gemma":[0.00008090975,0.0002007176,0.000246219,0.0001518107,0.0001405573,0.0001272226,0.0002057187,0.0007159219,0.0004275573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002888184,"about_ca_system_score_gemma":0.0002576374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008679024,"about_ca_topic_score_gemma":0.001131758,"domain_scores_codex":[0.9998704,0.00002015513,0.000007272743,0.00001408886,0.00002890533,0.000059099],"domain_scores_gemma":[0.9999278,0.00001297613,0.00001090484,0.00001511503,0.00000892819,0.00002441466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000125263,0.00003793956,0.0000715608,0.00001949346,0.000003545814,0.00003097311,0.00001470649,0.00005763957,0.9984285,0.0001346778,0.0000697002,0.001006099],"study_design_scores_gemma":[0.00002361846,0.0002028945,0.00212802,0.00000289288,0.00001323392,0.0001592156,0.00001593489,0.0008681851,0.9935926,0.00003181611,0.002958402,0.000003228069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956706,0.001125791,0.0009549934,0.0001050034,0.00003253275,0.00001662514,0.0002059792,0.00008315171,0.001805471],"genre_scores_gemma":[0.9957964,0.0005709791,0.0006548496,0.00003345145,0.00001212914,0.0000263469,0.0003458624,0.00001962012,0.002540349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001274183,"threshold_uncertainty_score":0.004262507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01861485806346799,"score_gpt":0.3140553090916353,"score_spread":0.2954404510281674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}