{"id":"W2121551257","doi":"10.1124/mol.63.4.821","title":"Unexpected Induction of the Human Connexin 43 Promoter by the Ras Signaling Pathway Is Mediated by a Novel Putative Promoter Sequence","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Molecular biology; Biology; Promoter; Transcription factor; Signal transduction; Kinase; Transcription (linguistics); Transcriptional regulation; Gene; Cell biology; Gene expression; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002537775,0.0003256633,0.0002908741,0.0002034239,0.0002462272,0.0002929134,0.0001798156,0.000284753,0.0009136068],"category_scores_gemma":[0.000226153,0.0002558098,0.0005015858,0.00009909554,0.0003462308,0.0001868096,0.0002292025,0.0007919182,0.0005809792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003132131,"about_ca_system_score_gemma":0.0003967393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003942923,"about_ca_topic_score_gemma":0.0007340575,"domain_scores_codex":[0.9998541,0.000025806,0.0000112432,0.00004384754,0.00002842163,0.00003664871],"domain_scores_gemma":[0.9997273,0.00009084823,0.0000518172,0.0000378315,0.00002695432,0.00006525536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006557372,0.000007806683,0.00007242252,0.00001290547,0.000001821002,0.00008208855,0.00001095411,0.00002946908,0.9988526,0.0003261378,0.00001388348,0.0005243366],"study_design_scores_gemma":[0.00002042241,0.0001380551,0.002043226,0.000007037338,0.00001071331,0.0004867124,0.00001851566,0.0009238989,0.9943428,0.0002122731,0.001789926,0.000006450838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9694837,0.001303365,0.02673724,0.0002697353,0.00008086661,0.00005022266,0.0003832917,0.0002436161,0.001447893],"genre_scores_gemma":[0.9856229,0.0004471029,0.01140497,0.00008460689,0.00004157206,0.00004115973,0.0007592121,0.00004891607,0.001549572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009136068,"threshold_uncertainty_score":0.003056347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01969787290620661,"score_gpt":0.2861588377911386,"score_spread":0.266460964884932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}