{"id":"W2121608455","doi":"10.1095/biolreprod.104.035238","title":"Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation1","year":2004,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"","keywords":"Methylenetetrahydrofolate reductase; Betaine; Biology; Infertility; Reductase; Male infertility; Genetics; Internal medicine; Endocrinology; Physiology; Andrology; Pregnancy; Enzyme; Biochemistry; Gene; Allele; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003791857,0.000898845,0.000735282,0.00125837,0.0003491532,0.0003715019,0.000495162,0.0008920026,0.00355559],"category_scores_gemma":[0.0002581799,0.0006160916,0.0004232264,0.0002991092,0.0005504723,0.0003325811,0.0003465758,0.0009419301,0.001204442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002368802,"about_ca_system_score_gemma":0.0002280981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006133503,"about_ca_topic_score_gemma":0.00103726,"domain_scores_codex":[0.999705,0.0000516293,0.00003409405,0.000075804,0.00008249292,0.00005095466],"domain_scores_gemma":[0.9993194,0.00006091589,0.0003139908,0.00006065236,0.00003505345,0.0002099404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003394774,0.00007587996,0.0006219163,0.00005443212,0.00001616242,0.0001935007,0.00005206829,0.00003338421,0.9957982,0.0001669814,0.0001401206,0.002507833],"study_design_scores_gemma":[0.0002365887,0.003146566,0.0396864,0.00007508144,0.0001491946,0.003860124,0.0001242388,0.0007482164,0.9411927,0.0003682497,0.0103777,0.00003483579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792386,0.006948043,0.006948835,0.0005468936,0.0001079152,0.00006698811,0.0020211,0.001081194,0.003040431],"genre_scores_gemma":[0.9622076,0.006326797,0.007583574,0.0003339357,0.0001196372,0.0001422399,0.002338702,0.0004023097,0.02054526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00355559,"threshold_uncertainty_score":0.01189464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02777222245590433,"score_gpt":0.331532635859599,"score_spread":0.3037604134036947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}