{"id":"W2121608455","doi":"10.1095/biolreprod.104.035238","title":"Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation1","year":2004,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"","keywords":"Methylenetetrahydrofolate reductase; Betaine; Biology; Infertility; Reductase; Male infertility; Genetics; Internal medicine; Endocrinology; Physiology; Andrology; Pregnancy; Enzyme; Biochemistry; Gene; Allele; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008841145,0.0001695294,0.000357499,0.0002348724,0.0000606867,0.000005047909,0.00009809988,0.0001651502,0.000805805],"category_scores_gemma":[0.0003056423,0.0001523122,0.00008856528,0.0004699414,0.0002441231,0.0001007353,0.00005502701,0.0002270821,0.00007481523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001287446,"about_ca_system_score_gemma":0.000139388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001195539,"about_ca_topic_score_gemma":0.00004745357,"domain_scores_codex":[0.9979779,0.0001452894,0.0005886715,0.0007227594,0.000204979,0.0003604375],"domain_scores_gemma":[0.9989952,0.00002311722,0.0001396715,0.0005379486,0.0002092312,0.00009484613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000887838,0.0008996155,0.03124808,0.00009727346,0.0001105388,0.00001198125,0.0004271642,0.00007174088,0.9537567,0.00001161384,0.003762538,0.008714878],"study_design_scores_gemma":[0.003283423,0.002106581,0.09840282,0.00006049963,0.00007613814,0.00007190007,0.0001703444,0.00007767641,0.8749679,0.0002553769,0.02031137,0.000216017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837341,0.005236498,0.00003959783,0.01001441,0.0001552911,0.0005846521,0.00008353948,0.00003653845,0.00011538],"genre_scores_gemma":[0.9956409,0.000846166,0.0008643723,0.0001017477,0.0001098759,0.00003094633,0.001059715,0.00001496502,0.001331259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07878888,"threshold_uncertainty_score":0.8823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02777222245590433,"score_gpt":0.331532635859599,"score_spread":0.3037604134036947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}