{"id":"W2121682207","doi":"10.1002/pros.20912","title":"Over‐expression of IκB‐kinase‐ε (IKKε/IKKi) induces secretion of inflammatory cytokines in prostate cancer cell lines","year":2009,"lang":"en","type":"article","venue":"The Prostate","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"Université de Montréal; Prostate Cancer Foundation","keywords":"Prostate cancer; LNCaP; IκB kinase; Cancer research; Cytokine; Interleukin 6; Prostate; Cancer; Inflammation; Metastasis; Secretion; Proinflammatory cytokine; Medicine; Internal medicine; Biology; Endocrinology; NF-κB","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002231166,0.0004889244,0.0003092286,0.0003074267,0.0002359533,0.0003770581,0.000277935,0.0002360345,0.001916656],"category_scores_gemma":[0.00009744565,0.000157658,0.0004620399,0.0004436583,0.0002685476,0.0001807647,0.0002016167,0.0009888532,0.0007585121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004188194,"about_ca_system_score_gemma":0.0003738844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009879777,"about_ca_topic_score_gemma":0.00106729,"domain_scores_codex":[0.9997428,0.0000235296,0.00003669243,0.00003751732,0.00009437538,0.00006500723],"domain_scores_gemma":[0.9998595,0.00002444945,0.00003522968,0.00002786066,0.00001505436,0.00003796536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001141032,0.0001116138,0.000267479,0.00007391965,0.000009973912,0.00005922919,0.00001933218,0.00007886646,0.9984958,0.00005840732,0.000107727,0.0006034205],"study_design_scores_gemma":[0.00003156171,0.0006621787,0.003940064,0.00001054707,0.0000316696,0.0003554552,0.00005029575,0.0007889413,0.9910592,0.00003311105,0.003029809,0.000007107724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867041,0.003513537,0.00491999,0.0002001983,0.0001499447,0.00009572787,0.001793118,0.0002888301,0.002334565],"genre_scores_gemma":[0.9881542,0.002068707,0.003119505,0.0000951598,0.00002657595,0.0001317872,0.003113473,0.00003317941,0.003257348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001916656,"threshold_uncertainty_score":0.00641185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008197415785452569,"score_gpt":0.2456484266592755,"score_spread":0.2374510108738229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}