{"id":"W2121688787","doi":"10.1128/iai.00778-07","title":"<i>Lactobacillus rhamnosus</i> Strain GG Prevents Enterohemorrhagic <i>Escherichia coli</i> O157:H7-Induced Changes in Epithelial Barrier Function","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation","keywords":"Lactobacillus rhamnosus; Microbiology; Tight junction; Biology; Barrier function; Probiotic; Intestinal mucosa; Escherichia coli; Caco-2; In vitro; Bacteria; Cell biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002797866,0.000182477,0.0001737336,0.00007632378,0.0002541343,0.00001858894,0.00006633679,0.0002254218,0.00006173238],"category_scores_gemma":[0.00004273085,0.000184869,0.00005695492,0.0001351214,0.00006806695,0.00001271808,0.00007155889,0.0002779821,0.00001273189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003771949,"about_ca_system_score_gemma":0.00008555143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009407741,"about_ca_topic_score_gemma":0.001650934,"domain_scores_codex":[0.9989402,0.0002459301,0.0002071901,0.0002597163,0.00007558116,0.000271415],"domain_scores_gemma":[0.9995195,0.000009890305,0.00008725443,0.0002297939,0.00005233171,0.0001012096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001468389,0.0001444137,0.02299955,0.00002908639,0.00001958807,0.000002126344,0.0001701652,0.000002577034,0.9735505,0.00000379214,0.0002599866,0.002671409],"study_design_scores_gemma":[0.002700429,0.001353136,0.6320222,0.00004015394,0.00002547139,0.0001192849,0.0001357559,0.0000291226,0.3146741,0.0000346967,0.04844066,0.0004249679],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998085,0.0001642074,0.0002029003,0.00009714474,0.0004947173,0.0002714258,0.00004647157,0.00002453954,0.0006135674],"genre_scores_gemma":[0.9970828,0.001045816,0.00002681705,0.001030938,0.0001570053,0.00002350966,0.0001479791,0.00001741681,0.0004676848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6588764,"threshold_uncertainty_score":0.7538737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01656508864461059,"score_gpt":0.2432295456311748,"score_spread":0.2266644569865642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}