{"id":"W2121728733","doi":"10.1093/carcin/bgi312","title":"Effects of folate deficiency on gene expression in the apoptosis and cancer pathways in colon cancer cells","year":2005,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Biology; Cancer research; DNA repair; Cancer; DNA damage; Apoptosis; Colorectal cancer; Cancer cell; Cell cycle; Gene; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002452696,0.0001284746,0.0002573697,0.0002145949,0.00004191537,0.000007609127,0.000113052,0.00009724592,0.00003283956],"category_scores_gemma":[0.00003175587,0.00008343402,0.00004889687,0.0003917726,0.00005435845,0.00004163079,0.00004172761,0.0001466457,0.000004115111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127666,"about_ca_system_score_gemma":0.00009589911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073357,"about_ca_topic_score_gemma":0.0002640208,"domain_scores_codex":[0.9988342,0.0001067249,0.0002031418,0.0002563439,0.0003088106,0.0002907806],"domain_scores_gemma":[0.9994617,0.0001779582,0.00004456345,0.0002071527,0.00004479191,0.00006380935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001755865,0.0001941172,0.04338255,0.0002476957,0.000006433438,0.00001930344,0.00133744,0.00007783064,0.9141638,0.000004098252,0.0001294844,0.04026164],"study_design_scores_gemma":[0.001073515,0.0002428655,0.1811229,0.0002300083,0.00002988018,0.000001301308,0.00009102592,0.0001545291,0.8168296,0.000003701078,0.0001493413,0.00007133576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874961,0.01136445,0.000002254706,0.0002928851,0.00005092789,0.0005600119,0.00001215184,0.000006597701,0.000214656],"genre_scores_gemma":[0.9936062,0.005718726,0.00005962152,0.0002692594,0.00006608103,0.0001966338,0.000002084822,0.00001549206,0.00006595829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1377403,"threshold_uncertainty_score":0.3402341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02399163091644745,"score_gpt":0.2904016713704718,"score_spread":0.2664100404540243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}