{"id":"W2121731147","doi":"10.1128/iai.72.7.4200-4209.2004","title":"<i>Mycobacterium bovis</i>BCG Urease Attenuates Major Histocompatibility Complex Class II Trafficking to the Macrophage Cell Surface","year":2004,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Genentech; Michael Smith Health Research BC; British Columbia Lung Association","keywords":"Intracellular; Biology; Microbiology; Mycobacterium bovis; Mycobacterium smegmatis; Intracellular parasite; Interferon gamma; Urease; Molecular biology; Biochemistry; Mycobacterium tuberculosis; Enzyme; In vitro; Tuberculosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001076361,0.0001732307,0.0001822927,0.00006082145,0.00007102868,0.0001920926,0.0001349229,0.0002098505,0.0009435702],"category_scores_gemma":[0.0001490679,0.00006027748,0.0001245216,0.00004771212,0.0001451193,0.0000976638,0.0001008302,0.0003498516,0.0003204696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002098551,"about_ca_system_score_gemma":0.000146137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086598,"about_ca_topic_score_gemma":0.001057817,"domain_scores_codex":[0.9998806,0.00003070082,0.00001140616,0.00001135398,0.00002868527,0.00003723591],"domain_scores_gemma":[0.9999118,0.00002004402,0.00002517922,0.00001041007,0.00001489445,0.00001774004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001625325,0.00002391193,0.000134397,0.00001881321,0.000002619202,0.00002751024,0.000004763038,0.00001921523,0.998912,0.00002886033,0.00003747266,0.0006279106],"study_design_scores_gemma":[0.00001482012,0.0006616265,0.003818359,0.00000788395,0.00000768388,0.0002201528,0.00001718702,0.0003906158,0.9931585,0.0000175654,0.001683765,0.000001843373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996379,0.001802339,0.0005741543,0.0001387965,0.00004243847,0.00000841994,0.00008419358,0.00004527765,0.0009254404],"genre_scores_gemma":[0.9971812,0.0005170695,0.000540881,0.000126465,0.00001983883,0.00001000206,0.0001791533,0.00001680846,0.001408682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001086598,"threshold_uncertainty_score":0.003156543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137382373798894,"score_gpt":0.3108248376016366,"score_spread":0.2794510138636477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}