{"id":"W2121758361","doi":"10.1086/652701","title":"Safety and Cross‐Reactive Immunogenicity of Candidate AS03‐Adjuvanted Prepandemic H5N1 Influenza Vaccines: A Randomized Controlled Phase 1/2 Trial in Adults","year":2010,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Q & T Research; Izaak Walton Killam Health Centre; Dalhousie University","funders":"GlaxoSmithKline; U.S. Department of Health and Human Services","keywords":"Immunogenicity; Reactogenicity; Adjuvant; Medicine; Influenza A virus subtype H5N1; Hemagglutinin (influenza); Vaccination; Virology; Antigen; Trivalent influenza vaccine; Influenza vaccine; Immunology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.003449084,0.0002852826,0.002413847,0.0004229468,0.0001795073,0.00003106967,0.0001804174,0.0001123104,0.00008234843],"category_scores_gemma":[0.01858386,0.0001518126,0.0005730933,0.0003029084,0.0006337816,0.0002649617,0.000103236,0.000858804,0.000001816265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000118677,"about_ca_system_score_gemma":0.0006082096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008070198,"about_ca_topic_score_gemma":0.0002720179,"domain_scores_codex":[0.9962896,0.0008933968,0.001763647,0.0001625088,0.0005660501,0.0003248264],"domain_scores_gemma":[0.9931242,0.003777175,0.001414387,0.0003243146,0.001139975,0.0002199376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.952,0.001090729,0.03618329,0.0001029965,0.001859019,0.00003140217,0.00123592,0.00004707355,0.006786371,0.00001676984,0.00002615596,0.0006202648],"study_design_scores_gemma":[0.9679974,0.001817531,0.02627808,0.0003924142,0.001375237,0.0001953774,0.0002258392,0.0003499831,0.0009414167,0.0002469756,0.00004545856,0.0001343101],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909953,0.005117228,0.00002632397,0.00007637063,0.0002739104,0.003152383,0.00006803708,0.00002224777,0.0002681355],"genre_scores_gemma":[0.9972839,0.002174471,0.000008124602,0.0001897607,0.0002462625,0.00005575808,0.000002655321,0.00002123034,0.00001788443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01599737,"threshold_uncertainty_score":0.989683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01319986654178698,"score_gpt":0.365457180197832,"score_spread":0.352257313656045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}